Valuation: ISIS Pharmaceuticals, Inc.

Market Cap 10.62B 9.31B 8.58B 7.93B 15.03B 1,013B 15.28B 102B 40.2B 499B 39.88B 39.01B 1,717B P/E 2026 *
-17.8x
P/E 2027 * -36.9x
Enterprise Value 10.37B 9.08B 8.38B 7.74B 14.67B 989B 14.92B 100B 39.25B 487B 38.93B 38.08B 1,676B EV / Sales 2026 *
11.7x
EV / Sales 2027 * 7.46x
Free-Float
99.09%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: ISIS Pharmaceuticals, Inc.

Manager TitleAgeSince
Investor Relations Contact 60 2012-06-30
Chief Executive Officer 64 2019-12-31
Director of Finance/CFO 64 2000-04-30
Director TitleAgeSince
Director/Board Member 64 2005-12-12
Director/Board Member 73 2002-04-30
Director/Board Member 64 2019-03-24
Change 5-day change 1-year change 3-year change Capi.($)
+1.33%+2.73% - - 10.62B
+0.58%+2.06%+2.92%+10.86% 50.44B
-2.22%-1.25%+385.40%+586.81% 40.63B
-0.54%+0.39%+25.57%-5.28% 34.88B
-1.36%+0.35%+17.88%+55.14% 33.67B
+1.21%-4.58%+3.00%+35.46% 26.29B
-1.81%-1.48% - - 17.11B
+0.51%-3.47%+63.97%+122.60% 15.29B
+0.23%-0.58%+13.76%+21.11% 13.74B
-0.62%-3.09%+10.29%-31.35% 12.93B
Average -0.27%-0.01%+65.35%+99.42% 27.22B
Weighted average by Cap. -0.42%+0.77%+81.98%+126.19%

Financials

2026 *2027 *
Net sales 889M 779M 718M 664M 1.26B 84.8B 1.28B 8.58B 3.37B 41.77B 3.34B 3.27B 144B 1.41B 1.24B 1.14B 1.05B 2B 135B 2.03B 13.63B 5.35B 66.38B 5.3B 5.19B 228B
Net income -594M -520M -480M -443M -841M -56.64B -855M -5.73B -2.25B -27.9B -2.23B -2.18B -96.02B -292M -256M -236M -218M -413M -27.83B -420M -2.82B -1.1B -13.71B -1.1B -1.07B -47.18B
Net Debt -252M -221M -204M -188M -357M -24.08B -363M -2.44B -956M -11.86B -948M -927M -40.82B -86.16M -75.48M -69.6M -64.31M -122M -8.22B -124M -831M -326M -4.05B -323M -316M -13.93B
Logo ISIS Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
Employees
-
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-