Valuation: Ionis Pharmaceuticals, Inc.

Capitalization 12.27B 10.56B 9.65B 9.21B 16.88B 1,177B 17.16B 116B 44.81B 559B 46.04B 45.05B 1,947B P/E ratio 2026 *
-20.8x
P/E ratio 2027 * -62.7x
Enterprise value 12.05B 10.37B 9.48B 9.04B 16.58B 1,156B 16.85B 114B 44B 549B 45.21B 44.24B 1,912B EV / Sales 2026 *
13.5x
EV / Sales 2027 * 8x
Free-Float
99.39%
Yield 2026 *
-
Yield 2027 * -
1 day-1.92%
1 week-1.95%
Current month-0.71%
1 month-3.37%
3 months-7.90%
6 months+3.75%
Current year-6.17%
1 week 73.32
Extreme 73.32
79.19
1 month 71.18
Extreme 71.175
79.19
Current year 68.9
Extreme 68.9
86.74
1 year 32
Extreme 32
86.74
3 years 23.95
Extreme 23.95
86.74
5 years 23.95
Extreme 23.95
86.74
10 years 19.59
Extreme 19.5927
86.74
Manager TitleAgeSince
Investor Relations Contact 60 2012-06-30
Chief Executive Officer 64 2019-12-31
Director of Finance/CFO 64 2000-04-30
Director TitleAgeSince
Director/Board Member 71 2000-08-31
Director/Board Member 81 1993-12-31
Director/Board Member 64 2005-12-12
Change 5d. change 1-year change 3-years change Capi.($)
-1.92%-1.95%+125.01%+104.83% 12.27B
-1.01%-2.82%-17.13%-19.68% 41.67B
-3.73%-6.04%+29.90%+22.07% 32.6B
-2.55%+2.71%+269.32%+448.83% 30.97B
-0.91%-5.37%+20.43%-11.67% 28.23B
-3.23%-4.84%+27.92%+22.28% 26.41B
-2.03%+0.77% - - 14.94B
+6.21%-2.39%+170.16%+4,385.95% 14.13B
-0.20%-0.10%+6.70%-2.02% 12.12B
-0.93%-2.06%+40.10%+96.92% 11.86B
Average -1.03%-1.86%+74.71%+560.84% 22.52B
Weighted average by Cap. -1.48%-2.17%+68.54%+373.13%

Financials

2026 *2027 *
Net sales 890M 766M 701M 668M 1.23B 85.43B 1.25B 8.4B 3.25B 40.55B 3.34B 3.27B 141B 1.48B 1.27B 1.16B 1.11B 2.03B 142B 2.07B 13.94B 5.39B 67.26B 5.54B 5.42B 234B
Net income -594M -511M -467M -446M -817M -56.96B -831M -5.6B -2.17B -27.04B -2.23B -2.18B -94.21B -199M -171M -156M -149M -273M -19.05B -278M -1.87B -725M -9.04B -745M -729M -31.5B
Net Debt -220M -190M -173M -165M -303M -21.14B -308M -2.08B -805M -10.03B -827M -809M -34.96B -460M -396M -362M -345M -633M -44.13B -643M -4.34B -1.68B -20.95B -1.73B -1.69B -72.99B
Logo Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
Employees
1,402
Date Price Change Volume
26-05-15 74.23 $ -1.92% 2,119,183
26-05-14 75.68 $ -2.47% 1,798,305
26-05-13 77.60 $ +2.33% 1,360,373
26-05-12 75.83 $ +0.60% 1,408,887
26-05-11 75.38 $ -0.44% 1,533,667
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
A
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
24
Last Close Price
74.23USD
Average target price
100.78USD
Spread / Average Target
+35.77%

Quarterly revenue - Rate of surprise