Company Valuation: Karyopharm Therapeutics Inc.

Data adjusted to current consolidation scope
Fiscal Period: December 2021 2022 2023 2024 2025 2026 2027 2028
Market Cap 1 485.8 384.9 99.07 85.34 134.8 36.29 - -
Change - -20.76% -74.26% -13.86% 57.91% -73.07% - -
Enterprise Value (EV) 426.4 277.1 99.07 85.34 134.8 36.29 36.29 36.29
Change - -35.03% -64.24% -13.86% 57.91% -73.07% 0% 0%
P/E -3.9x -1.68x -0.69x -1.07x -0.41x -0.33x -0.65x -0.98x
PBR -6.07x -16.7x - - - - - -
PEG - -0.1x 0x 0x -0x 0x 0x 0x
Capitalization / Revenue 2.32x 2.45x 0.68x 0.59x 0.92x 0.27x 0.21x 0.11x
EV / Revenue 0x 0x 0x 0x 0x 0.27x 0.21x 0.11x
EV / EBITDA - - - - - - - -
EV / EBIT -0x -0x -0x -0x -0x -0.37x -0.6x -13.7x
EV / FCF - - - - - - - -
FCF Yield - - - - - - - -
Dividend per Share 2 - - - - - - - -
Rate of return - - - - - - - -
EPS 2 -24.75 -30.3 -18.75 -9.45 -17.93 -4.7 -2.387 -1.575
Distribution rate - - - - - - - -
Net sales 1 209.8 157.1 146 145.2 146.1 135.6 173.6 332.3
EBITDA -97.48 -141.6 - - - - - -
EBIT 1 -98.27 -142.2 -129.5 -119.4 -90.71 -98.75 -60.21 -2.649
Net income 1 -124.1 -165.3 -143.1 -76.42 -196 -160.2 -114.9 -85.6
Net Debt -59.32 -107.9 - - - - - -
Reference price 2 96.450 51.000 12.975 10.144 7.360 1.540 1.540 1.540
Nbr of stocks (in thousands) 5,037 7,548 7,636 8,413 18,310 22,681 - -
Announcement Date 2/8/22 2/15/23 2/29/24 2/19/25 2/12/26 - - -
1USD in Million2USD
Estimates

P/E, Detailed evolution



P/E (Y) EV / Sales (Y) EV / EBITDA (Y) Dividend Yield (Y) Capi.($)
-0.34x - - - 36.29M
18.38x4.26x10.01x0.49% 79.26B
-17.5x26.14x-16.97x-.--% 58.56B
20.07x4.29x13.32x2.45% 58.62B
34.59x11.77x22.57x-.--% 48.75B
21.02x4.65x13.25x0.69% 46.32B
37.53x3.55x13.52x-.--% 32.12B
54.53x3.46x26.78x-.--% 24.77B
63.72x6.81x40.43x-.--% 21.5B
23.49x5.04x13.12x-.--% 15.97B
Average 25.55x 7.77x 15.11x 0.4% 38.59B
Weighted average by Cap. 22.21x 8.64x 11.59x 0.56%

Y-o-Y evolution of P/E

Historical PBR trend

Evolution Enterprise Value / Sales

Change in Enterprise Value/EBITDA


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