Valuation: Karyopharm Therapeutics Inc.

Market Cap 36.29M 31.45M 29.68M 26.92M 50.5M 3.48B 50.87M 354M 137M 1.76B 136M 133M 5.61B P/E 2026 *
-0.34x
P/E 2027 * -0.67x
Enterprise Value 36.29M 31.45M 29.68M 26.92M 50.5M 3.48B 50.87M 354M 137M 1.76B 136M 133M 5.61B EV / Sales 2026 *
0.27x
EV / Sales 2027 * 0.21x
Free-Float
95.33%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day-0.62%
1 week-10.61%
Current month-22.33%
1 month-20.79%
3 months-83.16%
6 months-79.62%
Current year-78.26%
1 week 1.24
Extreme 1.24
1.75
1 month 1.24
Extreme 1.24
2.14
Current year 1.24
Extreme 1.24
10.99
1 year 1.24
Extreme 1.24
10.99
3 years 1.24
Extreme 1.24
29.25
5 years 1.24
Extreme 1.24
220.95
10 years 1.24
Extreme 1.24
444.15
Manager TitleAgeSince
Chief Executive Officer 58 2021-05-02
Director of Finance/CFO 55 2025-01-02
Chief Tech/Sci/R&D Officer - 2023-03-31
Director TitleAgeSince
Director/Board Member 62 2012-12-31
Director/Board Member 61 2013-03-31
Director/Board Member 78 2013-10-02
Date Insider Type Main position Quantity % Market Cap. Importance
9/1/26 Sell

Controller/Auditor

-19 0.0001%
7/28/26 Sell

Executive/Senior Manager

-189 0.0008%
5/21/26 Free

Director

15,508 0.0688%
Change 5-day change 1-year change 3-year change Capi.($)
-0.62%-10.61%-75.19%-91.79% 36.52M
+1.57%-4.11%+41.74%-4.64% 78.04B
+1.89%+0.78%+523.95%+30.03% 57.48B
+0.16%-1.72%-15.98%-35.81% 57.4B
+0.35%-3.14%-11.03%+26.34% 48.81B
+2.38%+0.10%+1.49%+155.34% 45.5B
+0.10%-1.57%+50.05%-15.20% 32.08B
+0.59%-3.60%+47.04%+92.49% 24.62B
-0.62%-3.79%+0.84%+145.92% 20.77B
+2.24%-0.40%+66.12%+100.09% 15.75B
Average +0.62%-3.69%+62.90%+40.28% 38.05B
Weighted average by Cap. +0.78%-2.52%+94.11%+36.94%

Financials

2026 *2027 *
Net sales 136M 118M 111M 101M 189M 13B 190M 1.32B 510M 6.59B 509M 498M 20.96B 174M 150M 142M 129M 242M 16.64B 243M 1.7B 653M 8.44B 652M 638M 26.83B
Net income -160M -139M -131M -119M -223M -15.35B -225M -1.56B -603M -7.79B -602M -588M -24.76B -115M -99.56M -93.95M -85.23M -160M -11.01B -161M -1.12B -432M -5.59B -432M -422M -17.76B
Net Debt - -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
26-09-14 US$1.600 -0.62% 991,586
26-09-11 US$1.610 -0.62% 6,737,667
26-09-10 US$1.620 -4.14% 800,950
26-09-09 US$1.690 -1.74% 772,567
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
5
Last Close Price
1.600USD
Average target price
7.250USD
Spread / Average Target
+353.12%

Quarterly revenue - Rate of surprise

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