Valuation: Karyopharm Therapeutics Inc.

Market Cap 234M 206M 191M 176M 332M 22.41B 339M 2.28B 891M 11.01B 880M 861M 38.06B P/E 2026 *
-2.48x
P/E 2027 * -3.33x
Enterprise Value 487M 428M 397M 365M 690M 46.6B 705M 4.73B 1.85B 22.9B 1.83B 1.79B 79.15B EV / Sales 2026 *
3.55x
EV / Sales 2027 * 1.51x
Free-Float
95.32%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day-2.80%
1 week+4.69%
Current month+2.87%
1 month+5.79%
3 months+25.62%
6 months+22.64%
Current year+36.55%
1 week 9.29
Extreme 9.2901
10.86
1 month 8.78
Extreme 8.78
10.86
Current year 5
Extreme 5
10.99
1 year 3.65
Extreme 3.6503
10.99
3 years 3.51
Extreme 3.51
29.25
5 years 3.51
Extreme 3.51
220.95
10 years 3.51
Extreme 3.51
444.15
Manager TitleAgeSince
Chief Executive Officer 58 2021-05-02
Director of Finance/CFO 55 2025-01-02
Chief Tech/Sci/R&D Officer - 2023-03-31
Director TitleAgeSince
Director/Board Member 62 2012-12-31
Director/Board Member 61 2013-03-31
Director/Board Member 78 2013-10-02
Date Insider Type Main position Quantity % Market Cap.
05-20Free

Director

15,508 0.0688%
05-20Free

Director

15,508 0.0688%
05-20Free

Director

15,508 0.0688%
Change 5-day change 1-year change 3-year change Capi.($)
-2.80%+4.69%+120.88%-59.39% 234M
-0.22%+1.35%+16.79%-7.70% 67.61B
-0.63%-9.21%+37.82%+200.20% 51.6B
+0.36%+40.00%+40.00%+40.00% 43B
-1.26%-0.39%-49.63%-53.84% 40.94B
+4.96%-3.28%+55.75%-24.71% 29.4B
-1.85%-15.99%+99.20%-46.78% 27.09B
-2.12%-2.25%+66.54%+82.33% 23.32B
-0.67%+1.48%+10.61%+188.35% 19.92B
-2.12%-3.72%+61.37%+126.08% 16.91B
Average -0.98%-2.19%+45.93%+44.45% 32B
Weighted average by Cap. -0.60%-3.05%+31.03%+47.25%

Financials

2026 *2027 *
Net sales 137M 121M 112M 103M 194M 13.12B 198M 1.33B 522M 6.45B 515M 504M 22.28B 155M 136M 127M 116M 220M 14.85B 225M 1.51B 591M 7.3B 583M 570M 25.22B
Net income -121M -106M -98.59M -90.66M -171M -11.57B -175M -1.18B -460M -5.69B -454M -444M -19.66B -135M -118M -110M -101M -190M -12.86B -194M -1.31B -512M -6.32B -505M -494M -21.85B
Net Debt 253M 222M 206M 190M 358M 24.19B 366M 2.46B 962M 11.89B 950M 929M 41.09B -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
26-07-13 US$10.05 -2.80% 420,894
26-07-10 US$10.34 +1.37% 320,246
26-07-09 US$10.20 -4.40% 281,109
26-07-08 US$10.67 +6.17% 737,365
26-07-07 US$10.05 +4.47% 249,660
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
7
Last Close Price
10.05USD
Average target price
13.50USD
Spread / Average Target
+34.33%

Quarterly revenue - Rate of surprise

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