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Valuation: Karyopharm Therapeutics Inc.

Market Cap 204M 179M 165M 154M 290M 19.32B 292M 1.96B 764M 9.5B 767M 751M 33B P/E 2026 *
-2.17x
P/E 2027 * -2.91x
Enterprise Value 457M 400M 370M 345M 648M 43.23B 653M 4.39B 1.71B 21.25B 1.72B 1.68B 73.83B EV / Sales 2026 *
3.33x
EV / Sales 2027 * 1.32x
Free-Float
95.32%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day-0.67%
1 week-6.74%
Current month-1.21%
1 month+10.17%
3 months+34.98%
6 months+23.66%
Current year+22.15%
1 week 8.85
Extreme 8.85
9.83
1 month 8.22
Extreme 8.22
10.22
Current year 5
Extreme 5
10.99
1 year 3.65
Extreme 3.6503
10.99
3 years 3.51
Extreme 3.51
30.3
5 years 3.51
Extreme 3.51
220.95
10 years 3.51
Extreme 3.51
444.15
Manager TitleAgeSince
Chief Executive Officer 58 2021-05-02
Director of Finance/CFO 55 2025-01-02
Chief Tech/Sci/R&D Officer - 2023-03-31
Director TitleAgeSince
Director/Board Member 62 2012-12-31
Director/Board Member 61 2013-03-31
Director/Board Member 78 2013-10-02
Date Insider Type Main position Quantity % Market Cap.
05-20Free

Director

15,508 0.0688%
05-20Free

Director

15,508 0.0688%
05-20Free

Director

15,508 0.0688%
Change 5-day change 1-year change 3-year change Capi.($)
-0.67%-6.74%+107.62%-70.48% 204M
+0.21%-0.77%+19.20%-21.75% 62.05B
-0.84%-9.93%+57.21%+194.41% 54.52B
-5.75%+29.50%+29.50%+29.50% 41.55B
-2.96%+4.99%-53.01%-60.20% 39.06B
+1.22%+0.04%+59.29%-32.39% 29.02B
-7.06%+14.71%+132.96%-50.37% 25.38B
+5.31%+1.33%+53.64%+66.92% 19.62B
-1.05%-1.44%-3.02%+139.59% 16.89B
+1.04%+2.25%+60.69%+111.01% 15.89B
Average -1.05%+1.92%+46.41%+30.62% 30.42B
Weighted average by Cap. -1.40%+0.90%+34.68%+37.23%

Financials

2026 *2027 *
Net sales 137M 120M 111M 104M 194M 12.97B 196M 1.32B 513M 6.38B 515M 504M 22.15B 155M 136M 126M 117M 220M 14.68B 222M 1.49B 580M 7.22B 583M 570M 25.07B
Net income -121M -106M -97.82M -91.3M -171M -11.44B -173M -1.16B -452M -5.62B -454M -445M -19.53B -135M -118M -109M -101M -191M -12.71B -192M -1.29B -503M -6.25B -505M -494M -21.71B
Net Debt 253M 221M 204M 191M 358M 23.91B 361M 2.43B 945M 11.75B 950M 929M 40.84B -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
26-06-22 8.990 $ -0.33% 226,551
26-06-18 9.020 $ -4.04% 492,124
26-06-17 9.400 $ +3.30% 283,580
26-06-16 9.100 $ -5.60% 322,103
26-06-15 9.640 $ +1.47% 172,462
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
7
Last Close Price
9.020USD
Average target price
13.50USD
Spread / Average Target
+49.67%

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