Valuation: Ionis Pharmaceuticals, Inc.

Market Cap 9.9B 8.55B 8.05B 7.31B 13.76B 949B 13.96B 94.4B 36.99B 475B 37.18B 36.37B 1,581B P/E 2026 *
-16.4x
P/E 2027 * -31.5x
Enterprise Value 9.8B 8.46B 7.96B 7.24B 13.61B 939B 13.81B 93.42B 36.61B 470B 36.79B 36B 1,564B EV / Sales 2026 *
10.7x
EV / Sales 2027 * 7.1x
Free-Float
99.05%
Yield 2026 *
-
Yield 2027 * -
1 day+2.28%
1 week+5.00%
Current month+14.20%
1 month+8.31%
3 months+598.77%
6 months+598.77%
Current year+598.77%
1 week 48.33
Extreme 48.33
51.22
1 month 43.86
Extreme 43.86
51.22
Current year 43.86
Extreme 43.86
75.2
1 year 43.86
Extreme 43.86
75.2
3 years 43.86
Extreme 43.86
75.2
5 years 43.86
Extreme 43.86
75.2
10 years 43.86
Extreme 43.86
75.2
Manager TitleAgeSince
Investor Relations Contact 60 2012-06-30
Chief Executive Officer 64 2019-12-31
Director of Finance/CFO 64 2000-04-30
Director TitleAgeSince
Director/Board Member 64 2005-12-12
Director/Board Member 73 2002-04-30
Director/Board Member 64 2019-03-24
Change 5-day change 1-year change 3-year change Capi.($)
+2.28%+5.00% - - 9.74B
-0.11%-1.67%+1.80%+19.90% 48.84B
+1.89%+5.08%+492.59%+629.24% 45.44B
+1.83%+2.75%+15.61%+91.22% 41.22B
-0.50%-1.56%+24.67%+12.17% 39.71B
-2.74%-7.13%+18.72%+49.04% 32.6B
-1.14%-2.51%+27.52%+136.42% 16.67B
+0.59%-2.25% - - 16.25B
-0.49%-0.34%+3.45%+29.14% 14.08B
-2.60%-1.00%+77.85%+40.37% 13.68B
Average -0.10%-0.89%+82.78%+125.94% 29.83B
Weighted average by Cap. +0.06%-0.41%+104.17%+153.20%

Financials

2026 *2027 *
Net sales 913M 789M 742M 675M 1.27B 87.52B 1.29B 8.71B 3.41B 43.77B 3.43B 3.35B 146B 1.4B 1.21B 1.14B 1.04B 1.95B 134B 1.98B 13.37B 5.24B 67.19B 5.26B 5.15B 224B
Net income -602M -520M -490M -445M -837M -57.72B -849M -5.74B -2.25B -28.87B -2.26B -2.21B -96.16B -326M -281M -265M -241M -453M -31.22B -459M -3.11B -1.22B -15.62B -1.22B -1.2B -52.01B
Net Debt -103M -88.93M -83.67M -76.05M -143M -9.87B -145M -981M -385M -4.93B -387M -378M -16.43B 57.45M 49.62M 46.69M 42.43M 79.81M 5.5B 80.98M 548M 215M 2.75B 216M 211M 9.17B
Logo Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
Employees
1,480
Date Price Change Volume
26-08-18 €51.22 +2.28% 0
26-08-17 €50.08 +3.62% 0
26-08-14 €48.33 -0.49% 20
26-08-13 €48.57 -1.04% 60
26-08-12 €49.08 +0.62% 0
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
A
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
23
Last Close Price
59.62USD
Average target price
89.33USD
Spread / Average Target
+49.84%

Quarterly revenue - Rate of surprise