Valuation: Septerna, Inc.

Market Cap 2.28B 2.04B 1.87B 1.7B 3.22B 214B 3.3B 22.4B 8.93B 114B 8.56B 8.38B 360B P/E 2026 *
-36.2x
P/E 2027 * -21.4x
Enterprise Value 1.9B 1.7B 1.56B 1.42B 2.68B 178B 2.75B 18.67B 7.44B 95.35B 7.13B 6.98B 300B EV / Sales 2026 *
19.8x
EV / Sales 2027 * 24.5x
Free-Float
99.2%
Yield 2026 *
-
Yield 2027 * -
1 day+2.15%
1 week+15.56%
Current month+13.45%
1 month+30.10%
3 months+28.49%
6 months+111.79%
Current year+79.05%
1 week 42.22
Extreme 42.22
51.05
1 month 34.36
Extreme 34.36
51.05
Current year 22.78
Extreme 22.78
51.1
1 year 17.98
Extreme 17.98
51.1
3 years 4.17
Extreme 4.17
51.1
5 years 4.17
Extreme 4.17
51.1
10 years 4.17
Extreme 4.17
51.1
Manager TitleAgeSince
Chief Executive Officer 60 2021-10-31
Director of Finance/CFO 55 2025-01-05
President 58 2025-07-31
Director TitleAgeSince
Director/Board Member 60 2021-10-31
Chairman 50 2021-10-31
Director/Board Member 41 2021-10-31
Date Insider Type Main position Quantity % Market Cap. Importance
9/8/26 Free

Chief Technology Officer

275,000 0.5892%
9/1/26 Exercice

Executive/Senior Manager

9,999 0.0214%
8/12/26
RA Capital Management LP
SellCompany -1,493,000 3.3122%
Change 5-day change 1-year change 3-year change Capi.($)
+1.83%+15.56%+175.80% - 2.28B
+2.24%+5.83%+58.47%+65.65% 66.7B
+4.66%+8.90%+14.57%+85.41% 56.88B
-0.60%+1.73%+23.48%+94.40% 56.53B
+2.69%+16.12%+27.43%+121.31% 46.49B
+2.58%+8.09%+31.12%+45.57% 44.8B
+4.30%+6.54%+219.58%+901.35% 41.59B
-0.47%+9.60%+27.53%+52.88% 35.35B
+3.80%-1.00%+95.20%+66.79% 33.29B
+0.66%+5.25%-40.05%+391.25% 25.1B
Average +2.28%+4.06%+63.31%+202.73% 40.9B
Weighted average by Cap. +2.38%+4.00%+52.31%+181.09%

Financials

2026 *2027 *
Net sales 96.09M 85.77M 78.92M 71.63M 136M 9.01B 139M 944M 376M 4.82B 361M 353M 15.19B 73.66M 65.75M 60.5M 54.91M 104M 6.9B 107M 724M 288M 3.7B 276M 271M 11.64B
Net income -61.3M -54.71M -50.35M -45.69M -86.6M -5.75B -88.75M -602M -240M -3.08B -230M -225M -9.69B -115M -103M -94.52M -85.79M -163M -10.79B -167M -1.13B -451M -5.77B -432M -423M -18.19B
Net Debt -380M -339M -312M -283M -537M -35.62B -550M -3.73B -1.49B -19.07B -1.43B -1.4B -60.06B -476M -425M -391M -355M -673M -44.64B -690M -4.68B -1.87B -23.9B -1.79B -1.75B -75.28B
Projected Income Statement - Annual - Septerna, Inc.
Logo Septerna, Inc.
Septerna, Inc. is a clinical-stage biotechnology company. The Company is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. It is advancing programs in endocrinology, immunology and inflammation, metabolic diseases and additional therapeutic areas, both independently and with partners. The Company's Native Complex Platform is designed to enable it to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. It is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with significant unmet needs. It is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.
Employees
123
Date Price Change Volume
26-11-09 US$50.05 +2.45% 474,332
26-11-06 US$48.85 +3.17% 384,550
26-11-05 US$47.35 -1.11% 533,994
26-11-04 US$47.88 +9.57% 604,924
26-11-03 US$43.70 +1.16% 307,511
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BB
MarketScreener Ratings - Septerna, Inc.
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
10
Last Close Price
48.85USD
Average target price
56.78USD
Spread / Average Target
+16.23%

Quarterly revenue - Rate of surprise

Rate of surprise - Net sales - Quarterly - Septerna, Inc.
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