M3, Inc. Presentation Material

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The following presentation contains forecasts, plans, management targets, and other forward-looking projections relating to M3, Inc. and/or its group. These statements are drawn from assumptions of future events based on data currently available to us, and there exist possibilities that such assumptions are objectively incorrect and/or may produce differing actual results from those mentioned in the statements.

Furthermore, information and data other than those concerning the Company and its subsidiaries/affiliates are quoted from public information, and the Company has not verified and will not warrant their accuracy or dependability.

This presentation is provided for informational purposes only and does not constitute an offer or solicitation to buy or sell any securities. Any investment decisions should be made at your own discretion and responsibility.

M3, Inc.

Revenue growth excluding COVID-related items:

+29%, comparable

Unit: JPY MM

FY2024 Q1 - Q3

FY2025 Q1 - Q3

YoY

Revenue

205,521

264,395

+29%

Operating profit

50,101

62,346

+24%

Profit before tax

52,513

64,331

+23%

Profit

35,535

45,237

+27%







Solid performance continues in both revenue and profits.

An approx. JPY 4bn gain on the sale of the associate shares also contributed

FY2025 Q1-Q3 Consolidated Results

Unit: JPY MM

175,155 179,189

20,8008,400

205,521

2,700

264,395

2,200

+29%

COVID-related

(clinical trials, vaccination support, promotion of therapeutic drugs and vaccines, etc.)

Regular Businesses

FY2022 Q1-Q3

FY2023 Q1-Q3

FY2024 Q1-Q3

FY2025 Q1-Q3

Growth in the regular business accelerated in addition to the subsiding impact of COVID-related sales decline

* FY2024 Actuals: Q1 ~1.1 Bn, Q2 ~0.9 Bn, Q3 ~0.8 Bn, Q4 ~0.5 Bn

FY2025 Actuals: Q1 ~1.1 Bn, Q2 ~0.5 Bn, Q3 ~0.5 Bn

Consolidated Revenue Trend and COVID Impact

Before COVID

During COVID

Repercussion

Normalized

20km/h

20km/h

20km/h

20km/h

Organic Growth Rate



COVID-19

Impact

20km/h

20km/h



In Total…



20km/h 40km/h 0km/h 20km/h

Status per Segment

MP



ES



CS



SS



Overseas



Each segment and business was in a different phase, and the outlook for the growth rate also varied

* Please refer to the slide titled "Abbreviations of Segment Names" for the definitions of the segment abbreviations used in this presentation

Growth Dynamics and COVID Effects: FY2024



Before COVID

During COVID

Repercussion Normalized

Organic Growth Rate

20km/h

20km/h

20km/h

20km/h

COVID-19

Impact



20km/h

0km/h

In Total…



20km/h 40km/h

20km/h

20km/h

Status per Segment

MP



ES



CS



SS



Overseas



PS



The negative impact on COVID-related sales concluded in FY2024, with a return to baseline growth reflected in performance from FY2025

Growth Dynamics and COVID Effects: FY2025

Each business performed generally solidly

US clinical trials: vaccine-related projects were negatively affected by policy shifts

Unit: JPY MM

FY2024 Q1-Q3

FY2025 Q1-Q3

YoY

Domestic

Medical Platform

Revenue

68,397

81,833

+20%

Profit

25,977

30,047

+16%

Evidence Solution

Revenue

18,119

18,481

+2%

Profit

3,150

3,947

+25%

Career Solution

Revenue

16,058

17,872

+11%

Profit

4,777

4,849

+1%

Site Solution

Revenue

34,562

40,170

+16%

Profit

4,576

3,165

-31%

Patient Solution

Revenue

8,462

42,020

+397%

Profit

145

1,626

Emerging Businesses

Revenue

1,836

1,695

-8%

Profit

716

4,770

+566%

Overseas

Revenue

60,942

65,568

+8%

Profit

12,593

15,027

+19%



FY2025 Q1-Q3 Consolidated Results by Segment

Solid momentum in both businesses of pharma marketing and DX of the clinical scene

Order backlog: JPY 35.6 Bn

Improved revenue mix led to OP growth exceeding that of revenue

The business for pharmacists primarily drove revenue growth

OP growth decelerated due to changes in the service mix

Revenue: increased due to acquisition effects and steady topline growth in the existing businesses

OP: Losses associated with the start-up phase of new facilities were recorded

Gain on the sale of the associate shares: approx. JPY 4 Bn









Initial Forecasts MP

ES CS SS PS

Overseas

Other / Adjustments

FY2025 Q1-Q3 Act

Revenue Operating profit





268.0 Bn

264.4 Bn

53.0 Bn

62.3 Bn

In addition to MP and Overseas, the "Other / Adjustments", which recorded a gain on the sale of the associate shares, drove the upside in profits

* Please refer to the slide titled "Abbreviations of Segment Names" for the definitions of the segment abbreviations used in this presentation

FY2025 Q1-Q3 Forecasts vs. Actuals

M3's Triple Growth Engine + CSV

Growth Engine 1: Ecosystem Expansion (Sagrada Familia)

FY : 2010 2015 2020 2024

Country 3 82.5x 113.5x 186.0x

Business Types 6 152.5x 356.0x 417.0x

Business Units

(Type x Country)

10 242.5x 565.5x 808.0x

Sales (Bn) 14.6 64.74.5x 169.212.0x 284.919.5x

Aggressive M&A to ensue in reaching growth potentials exceeding 10~20x current levels

Business Scope Expansion and Growth Potential

15*

4**

2

2

Domestic Overseas

6

7

6

6

9

10

3

5

5

11

11



FY2021 FY2022 FY2023 FY2024 FY2025 at Q3

Earnings Release

Continuously conduct approximately 10 M&As annually. The pace of acquisition considerations remained at the same level as before. No changes were made to the fundamental strategy

* 2 out of 9 domestic deals, and 3 out of 6 overseas deals were conducted by listed subsidiaries

** 1 out of 2 overseas deals was conducted by a listed subsidiary

Trend in M&A Volume: Programmatic M&A Strategy



Growth Engine 2: Individual Business Development



Pharmaceutical Sales & Marketing DX

10 years ago

Present

Future

M3's Role

TAM

down by ~300 Bn yen



Industry productivity improvement from DX

MR

Related Costs

Internet

99%

1.5 Tn yen

1%

95%

1.15 Tn yen

5%

7080%

700

800 Bn yen

2030%

(2) MR Activity DX Support



(1) Internet Marketing

Support

(3) Data-driven Marketing Support

15 Bn yen 70 Bn yen 200 300 Bn yen

M3 involvement is to go beyond the bounds of the internet to improve productivity across the entire industry

Ref: M3 survey and estimate; numbers are approximate

Pharma Marketing Cost and TAM for M3

(10,000)

7

6

5

Historical Peak



65,752 MRs

-950

-1,095 -522



-752

-2,533

-2,742

-3,572

-1,738

-2,166

43,646 MRs in FY2024

(Second largest decline ever)

-2,963

-3,073

4

2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

In addition to a decrease in the number of MRs, an increasing number of contract reps and online reps who work exclusively online or by phone.... The trend toward sales efficiency is expected to continue

* Source: MR Certification Center "2025 MR White Paper"

Trend of Domestic Pharmaceutical Sales Reps (MRs)



Overall Trend

COVID-19

Sales

During COVID After COVID

Future

Now

Initiatives for Regrowth

Shift the focus from channel-centric pitches back to problem-solving proposals that tackle client challenges, and reinforce this approach

Key Initiatives:

Approaches to core pharmaceutical challenges

Further advancement of data-driven marketing

Providing a holistic solution through a mix of services

The proposal-capability program rolled out in FY2024 is now bearing fruit, and we will accelerate true digital transformation as a strategic partner to pharma clients

As a Strategic Partner to Pharma Companies

DX of the Clinical Scene



Number of Medical Institutions Using M3 DigiKar

9,100

The cumulative number of installations is approx. 9,100. Steady progress

Co-selling with DigiKarSmart further increases the added value of DigiKar



FY15 16 17 18 19 20 21 22 23 24 25

Incontestable #1 market share within cloud-based digital health records, approx. 430 million charts

M3 DigiKar EHR Growth

Physical

Medical Institutions

Online

Appointment

Next

Appointment

Auto-

Reception

M3 DigiKar Smart

Payment

Consultation

Linking to

EHR



Managing System





Patients

Mobile App



81,000 reviews with a rating of 4.6 from users, a new patient experience created, and a high rating in the category

* Taken from the following URL, as of January 26, 2026

https://apps.apple.com/jp/app/m3%E3%83%87%E3%82%B8%E3%82%AB%E3%83%AB%E3%82%B9%E3%83%9E%E3%83%BC%E3%83%88%E8%A8%BA%E5

%AF%9F%E5%88%B8/id1563102530

DX of Clinics DigiKar Smart

Unit: Index with FY2021Q3 as 1

17,446

13,201

11,400

10,042

9,437

7,089

5,673

4,3204,741

2,067

2,973

1

1,0701,368

44 173 479

Rapid market penetration of DigiKar Smart as the clinics' infrastructure # of Users: 1.8x YoY Txn Amount:2.0x YoY

Video call has been added and is expanding as an infrastructure for telemedicine



Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3

FY21

FY22

FY23

FY24

FY25

* Quarterly sum of monthly UUs

No. of DigiKar Smart Users

Unit: Index with FY2024Q1 - Q3 as 100

Sales of Medical Data Business*

122

100

Approx.

1.2x



FY2024 Q1 - Q3

FY2025 Q1 - Q3

Medical data business (actual medical practice, physician practice standards, etc.) also grew significantly along with the increase in the volume of data accumulated. Steady creation of ecosystem synergies

* Target: Real World Data, Estimation related services (part of Pharmaceutical Marketing business)

Ecosystem Synergy: Medical Data Business

Medical AI Platform





Analysis results accessible from viewers (e.g. PACS)

Medical Institutions

Send data

Hospital-based M3 Edge Server deployment

Receive analysis results by AI



M3 AI's Platform

Multiple participating vendors provide

cloud-based AI solutions, enabling continuous performance improvement

Currently providing the following services:

Chest CT

Chest X-ray

Head CT

Head MRI

Trunk CT

Allows to choose the best-fit AI per anatomy and condition, with the business model of pay-per-use system for medical institutions

Enabling easy access to a diverse range of high-quality AI, aim to improve diagnostic accuracy and productivity, thereby supporting the operational efficiency of medical institutions

* M3 AI is a joint venture between PSP Corporation and M3

Medical AI Platform Business by M3 AI


Analyzed Images

Image

AI Findings

Specific Services

Chest CT



Pulmonary Nodule

VUNO Med-LungCT

VUNO Med-LungCT (with time-series analysis)

Chest X-ray



Pulmonary Nodule and Other Findings

EIRL X-Ray Lung nodule (pulmonary nodule)

EIRL Chest Screening (pulmonary nodule, infiltrative shadow, atelectasis, interstitial shadows, CTR, etc.)

BMAX (Fibrotic ILD)

Head MRA



Cerebral Aneurysm

EIRL Brain Aneurysm

Head CT



Stroke

Stroke Basic Package (hemorrhagic, ischemic)

Trunk CT



Bone Temporal Subtraction

Temporal Subtraction For Bone

Cardiac Echo



Automated Measurement

Us2.ai (automated measurement of 65 items and cardiac function evaluation)



MRI NEW



MR Image Reconstruction

SwiftMR (MR image reconstruction software)

AI Platform Solutions (examples)

Overseas





Ratio of doctor members

(As of June 2025)



Including regions not shown above, more than 7 million doctor members and panelists, covering 50% of doctors worldwide

*The no. of doctors in Japan is based on data from the Ministry of Health, Labour and Welfare (2022). The no. of doctors in other countries is based on the latest data from WHO and other sources.

Number of Doctor Members and Panelists (Global)



Unit: JPY MM

North America

Europe

65,559

60,914

23,004

23,333

28,656

25,653

Growth Rate

+8%

-1%

+12%

North America

+1% at constant currency

Clinical Trials: vaccine-related projects in Q3 were affected by policy shifts

Europe

Remained solid, primarily in France, alongside the contribution from acquisitions

APAC

and others

11,927

FY2024 Q1-Q3

13,900

FY2025 Q1-Q3

+17%

APAC

+24% at constant currency

Contribution from Limbic acquisition

Segment profit increased +19%, driven by solid revenue and an improved sales mix

Overseas Segment: Sales by Region

Growth Engine 3: Ecosystem Synergy Creation





FY : 2010 2015 2020 2024

Country 3 82.5x 113.5x 186.0x

Business Types 6 152.5x 356.0x 417.0x

Business Units

(Type x Country)

10 242.5x 565.5x 808.0x

Sales (Bn) 14.6 64.74.5x 169.212.0x 284.919.5x

Business Scope Expansion and Growth Potential

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Disclaimer

M3 Inc. published this content on February 04, 2026, and is solely responsible for the information contained herein. Distributed via Public Technologies (PUBT), unedited and unaltered, on February 04, 2026 at 06:54 UTC.