Valuation : Spyre Therapeutics, Inc.

Market Cap 7.85B 6.75B 6.35B 5.8B 10.85B 741B 10.88B 75.06B 29.13B 380B 29.46B 28.82B 1,224B P/E 2026 *
-30.4x
P/E 2027 * -24.3x
Enterprise Value 7.39B 6.36B 5.98B 5.47B 10.22B 698B 10.25B 70.7B 27.43B 358B 27.75B 27.15B 1,153B EV / Sales 2026 *
-
EV / Sales 2027 * -
Free-Float
89.36%
Yield 2026 *
-
Yield 2027 * -
1 week-6.33%
Current month-1.99%
1 month-18.68%
3 months+10.45%
6 months+111.43%
Current year+170.07%
1 week 74
Extreme 74
76.5
1 month 74
Extreme 74
92.5
Current year 25.4
Extreme 25.4
92.5
1 year 12.3
Extreme 12.3
92.5
3 years 10.3
Extreme 10.3
92.5
5 years 10.3
Extreme 10.3
92.5
10 years 10.3
Extreme 10.3
92.5
Manager TitleAgeSince
Chief Executive Officer 36 2023-11-26
Director of Finance/CFO 49 2023-08-31
Chief Tech/Sci/R&D Officer - 2023-11-26
Director TitleAgeSince
Director/Board Member 36 2023-11-26
Director/Board Member 39 2023-06-21
Director/Board Member 36 2023-06-21
Change 5-day change 1-year change 3-year change Capi.($)
0.00%-6.33% - - 7.85B
-1.79%-2.27%+43.23%+88.96% 67.98B
-2.06%-0.18%+39.67%+86.44% 64.94B
-0.31%+6.54%-12.96%+378.92% 27.58B
+0.86%+1.65%-7.74%-14.95% 26.06B
-3.00%-2.90%+33.13%+12.54% 25.74B
-1.46%+0.42%+23.61%-18.61% 20.09B
-2.96%-15.21%+216.20%+368.10% 17.16B
-1.49%-4.88%-6.60%+531.89% 14.92B
-0.20%+8.37%+55.78%+164.98% 14.62B
Average -1.24%+0.26%+42.70%+177.58% 31.01B
Weighted average by Cap. -1.48%+0.18%+38.37%+137.35%

Financials

2026 *2027 *
Net sales - -
Net income -260M -224M -210M -192M -359M -24.53B -360M -2.49B -965M -12.59B -976M -954M -40.55B -336M -289M -272M -249M -465M -31.74B -466M -3.22B -1.25B -16.29B -1.26B -1.23B -52.46B
Net Debt -456M -392M -369M -337M -630M -43.02B -632M -4.36B -1.69B -22.07B -1.71B -1.67B -71.1B -565M -486M -457M -418M -782M -53.35B -784M -5.41B -2.1B -27.37B -2.12B -2.08B -88.18B
Logo Spyre Therapeutics, Inc.
Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, specializing in long-acting antibodies and antibody combinations for inflammatory bowel disease (IBD) and rheumatic diseases. The Company's pipeline includes investigational extended half-life antibodies targeting a4b7, TL1A, and IL-23. It is advancing a pipeline of monoclonal antibodies (mAbs) for the treatment of IBD and other immune-mediated diseases. The Company's pipeline includes its SKYLINE Phase II platform trial evaluating SPY001, SPY002, SPY003, and pairwise combinations thereof in subjects with moderately to severely active UC and its SKYWAY basket trial evaluating SPY072 in three rheumatic diseases: rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA). SPY001 is a highly potent, highly selective, and humanized monoclonal immunoglobulin G1 investigational antibody designed to bind selectively to the a4b7 integrin being developed for the treatment of IBD (UC and CD).
Employees
125
Date Price Change
26-09-04 €74.00 0.00%
26-09-03 €74.00 -1.99%
26-09-02 €75.50 -0.66%
26-09-01 €76.00 +0.66%
26-08-31 €75.50 -4.43%
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
16
Last Close Price
88.98USD
Average target price
119.69USD
Spread / Average Target
+34.52%

Quarterly revenue - Rate of surprise