Valuation: Spyre Therapeutics, Inc.

Market Cap 8.28B 7.23B 6.69B 6.14B 11.62B 798B 11.82B 79.79B 31.34B 389B 31.08B 30.4B 1,345B P/E 2026 *
-30.6x
P/E 2027 * -27.8x
Enterprise Value 7.7B 6.73B 6.22B 5.71B 10.81B 742B 10.99B 74.2B 29.15B 362B 28.9B 28.27B 1,250B EV / Sales 2026 *
-
EV / Sales 2027 * -
Free-Float
89.17%
Yield 2026 *
-
Yield 2027 * -
1 day-8.15%
1 week-5.23%
Current month+3.16%
1 month+13.19%
3 months+36.97%
6 months+189.01%
Current year+197.45%
1 week 81.5
Extreme 81.5
89
1 month 75.5
Extreme 75.5
89
Current year 25.4
Extreme 25.4
89
1 year 12.3
Extreme 12.3
89
3 years 10.3
Extreme 10.3
89
5 years 10.3
Extreme 10.3
89
10 years 10.3
Extreme 10.3
89
Manager TitleAgeSince
Chief Executive Officer 36 2023-11-26
Director of Finance/CFO 49 2023-08-31
Chief Tech/Sci/R&D Officer - 2023-11-26
Director TitleAgeSince
Director/Board Member 36 2023-11-26
Director/Board Member 39 2023-06-21
Director/Board Member 36 2023-06-21
Change 5-day change 1-year change 3-year change Capi.($)
-8.15%-5.23% - - 8.28B
-3.42%+4.90%+61.15%+87.70% 55.98B
-0.05%-5.85%+54.36%+124.61% 53.69B
-2.14%-9.13%+2.74%+421.65% 23.29B
-0.47%-1.53%-18.61%-15.41% 23.15B
-5.29%-1.90%+31.59%-8.84% 20.58B
-0.29%-2.05%+34.41%-27.98% 17.76B
-4.55%-1.95%+192.65%+349.58% 16.09B
-5.99%-5.29%+27.26%+648.58% 15.93B
+0.23%-2.49%+24.26%+187.16% 14B
Average -3.05%-0.43%+45.54%+196.34% 26.72B
Weighted average by Cap. -2.44%-0.88%+46.20%+162.02%

Financials

2026 *2027 *
Net sales - -
Net income -273M -238M -220M -202M -383M -26.26B -389M -2.63B -1.03B -12.83B -1.02B -1B -44.28B -311M -272M -252M -231M -437M -30B -445M -3B -1.18B -14.65B -1.17B -1.14B -50.58B
Net Debt -580M -507M -469M -430M -814M -55.86B -828M -5.59B -2.2B -27.28B -2.18B -2.13B -94.18B -485M -424M -392M -360M -681M -46.72B -693M -4.67B -1.84B -22.82B -1.82B -1.78B -78.77B
Logo Spyre Therapeutics, Inc.
Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, specializing in long-acting antibodies and antibody combinations for inflammatory bowel disease (IBD) and rheumatic diseases. The Company's pipeline includes investigational extended half-life antibodies targeting a4b7, TL1A, and IL-23. It is advancing a pipeline of monoclonal antibodies (mAbs) for the treatment of IBD and other immune-mediated diseases. The Company's pipeline includes its SKYLINE Phase II platform trial evaluating SPY001, SPY002, SPY003, and pairwise combinations thereof in subjects with moderately to severely active UC and its SKYWAY basket trial evaluating SPY072 in three rheumatic diseases: rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA). SPY001 is a highly potent, highly selective, and humanized monoclonal immunoglobulin G1 investigational antibody designed to bind selectively to the a4b7 integrin being developed for the treatment of IBD (UC and CD).
Employees
112
Date Price Change
26-07-17 81.50 -8.43%
26-07-16 €89.00 +2.89%
26-07-15 €86.50 +5.49%
26-07-14 €82.00 -3.53%
26-07-13 €85.00 -1.16%
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
17
Last Close Price
94.12USD
Average target price
103.93USD
Spread / Average Target
+10.43%

Quarterly revenue - Rate of surprise