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Valuation: Denali Therapeutics Inc.

Market Cap 3.7B 3.23B 2.99B 2.8B 5.24B 349B 5.28B 35.44B 13.74B 172B 13.89B 13.59B 597B P/E 2026 *
-9.61x
P/E 2027 * -9.71x
Enterprise Value 3.03B 2.64B 2.44B 2.29B 4.29B 285B 4.31B 28.98B 11.23B 140B 11.36B 11.11B 488B EV / Sales 2026 *
73.8x
EV / Sales 2027 * 26.8x
Free-Float
90.08%
Yield 2026 *
-
Yield 2027 * -
1 day-0.77%
1 week+7.62%
Current month+10.79%
1 month+28.71%
3 months+18.03%
6 months+38.34%
Current year+41.19%
1 week 21.41
Extreme 21.41
24.65
1 month 18.18
Extreme 18.18
24.65
Current year 15.34
Extreme 15.34
24.65
1 year 12.58
Extreme 12.58
24.65
3 years 10.57
Extreme 10.57
33.33
5 years 10.57
Extreme 10.57
79.7
10 years 10.57
Extreme 10.57
93.94
Manager TitleAgeSince
Director of Finance/CFO 52 2022-04-30
Chief Executive Officer 50 2015-07-31
Chief Tech/Sci/R&D Officer - 2025-11-05
Director TitleAgeSince
Director/Board Member 50 2015-02-28
Chairman 66 2015-02-28
Director/Board Member 73 2015-03-31
Date Insider Type Main position Quantity % Market Cap.
06-02Free

Director

25,634 0.0162%
06-02Free

Director

25,634 0.0162%
06-02Free

Director

25,634 0.0162%
Change 5-day change 1-year change 3-year change Capi.($)
-0.77%+7.62%+65.44%-24.90% 3.7B
+1.44%-1.25%+63.52%+114.88% 55.19B
+4.60%+3.02%+58.20%+47.16% 45.75B
-1.44%+0.39%-12.94%-19.24% 22.98B
-2.69%-2.10%-3.68%+379.00% 20.76B
+3.22%-0.84%+27.88%-34.00% 16.26B
+0.58%+1.08%+16.73%-38.06% 15.42B
-1.01%-2.30%+27.42%+171.92% 13.05B
+4.95%+11.70%+123.63%+252.19% 12.45B
+3.07%+0.14%+29.37% - 12.37B
Average +1.19%+3.10%+39.56%+94.33% 21.79B
Weighted average by Cap. +1.59%+1.63%+41.33%+97.67%

Financials

2026 *2027 *
Net sales 41M 35.75M 33.11M 30.99M 58.13M 3.87B 58.48M 393M 152M 1.9B 154M 151M 6.61B 113M 98.68M 91.39M 85.55M 160M 10.68B 161M 1.08B 420M 5.26B 425M 416M 18.25B
Net income -481M -420M -389M -364M -682M -45.4B -686M -4.61B -1.79B -22.35B -1.81B -1.77B -77.59B -463M -404M -374M -350M -657M -43.73B -661M -4.44B -1.72B -21.52B -1.74B -1.7B -74.74B
Net Debt -674M -588M -545M -510M -956M -63.64B -962M -6.46B -2.5B -31.32B -2.53B -2.48B -109B -665M -580M -537M -502M -942M -62.72B -948M -6.37B -2.47B -30.87B -2.5B -2.44B -107B
Logo Denali Therapeutics Inc.
Denali Therapeutics Inc. is a biopharmaceutical company establishing a new class of biotherapeutics designed to cross the blood-brain barrier using its TransportVehicle platform. It is focused on building a portfolio of therapeutic candidates by investing in its TV franchises, i.e., Enzyme TV (ETV), Oligonucleotide TV (OTV), and Antibody TV (ATV), to advance programs for rare diseases, such as lysosomal storage diseases, and common diseases, such as Alzheimer's disease and Parkinson's disease. Its most advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (Hunter syndrome). TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for mucopolysaccharidosis IIIA (Sanfilippo syndrome type A), DNL593 (PTV:PGRN) for frontotemporal dementia-granulin, DNL628 (OTV:MAPT) for Alzheimer’s disease, and DNL952 (ETV:GAA) for Pompe disease. It is also pursuing opportunities in other disease areas including oncology.
Employees
507
Date Price Change Volume
26-06-18 23.31 $ -0.77% 2,518,393
26-06-17 23.49 $ +7.11% 2,605,205
26-06-16 21.93 $ -1.31% 1,455,915
26-06-15 22.22 $ +2.59% 1,448,823
26-06-12 21.66 $ +3.04% 2,189,156
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
19
Last Close Price
23.31USD
Average target price
33.93USD
Spread / Average Target
+45.57%

Quarterly revenue - Rate of surprise

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