Valuation: Denali Therapeutics Inc.

Market Cap 3.98B 3.41B 3.19B 2.92B 5.48B 381B 5.56B 37.72B 14.71B 191B 14.96B 14.63B 633B P/E 2026 *
-11x
P/E 2027 * -10.8x
Enterprise Value 3.27B 2.81B 2.62B 2.4B 4.51B 313B 4.57B 31.01B 12.09B 157B 12.3B 12.03B 521B EV / Sales 2026 *
53.8x
EV / Sales 2027 * 25x
Free-Float
90.03%
Yield 2026 *
-
Yield 2027 * -
1 day-0.12%
1 week+2.13%
Current month+8.25%
1 month+4.57%
3 months+29.12%
6 months+23.43%
Current year+50.94%
1 week 24.01
Extreme 24.01
25.7
1 month 22.63
Extreme 22.6275
25.74
Current year 15.34
Extreme 15.34
27.3
1 year 12.58
Extreme 12.58
27.3
3 years 10.57
Extreme 10.57
33.33
5 years 10.57
Extreme 10.57
56.8
10 years 10.57
Extreme 10.57
93.94
Manager TitleAgeSince
Director of Finance/CFO 52 2022-04-30
Chief Executive Officer 50 2015-07-31
Chief Tech/Sci/R&D Officer 58 2025-11-05
Director TitleAgeSince
Director/Board Member 50 2015-02-28
Director/Board Member 73 2015-03-31
Director/Board Member 68 2015-03-31
Date Insider Type Main position Quantity % Market Cap.
8/12/26 Don

Founder

-32,220 0.0203%
8/11/26 Sell

Founder

-2,857 0.0018%
6/3/26 Free

Director

25,634 0.0162%
Change 5-day change 1-year change 3-year change Capi.($)
-0.12%+2.13%+63.62%+7.09% 3.99B
-3.00%+0.33%+77.39%+109.41% 73.96B
+1.90%+23.53%+56.60%+97.76% 64.66B
+0.55%+1.64%-5.15%+471.68% 27.32B
+5.12%+25.22%+5.24%-0.82% 27.86B
+2.74%+11.55%+66.56%+27.34% 25.97B
+0.47%+6.22%+39.36%-12.38% 19.98B
+1.82%-3.11%+245.72%+423.83% 17.84B
+0.94%+2.38%+24.83%+552.12% 16.24B
+0.73%+5.54%+39.71%+153.07% 13.3B
Average +1.12%+7.07%+61.39%+182.91% 29.11B
Weighted average by Cap. +0.67%+8.66%+60.02%+159.15%

Financials

2026 *2027 *
Net sales 60.84M 52.12M 48.77M 44.64M 83.78M 5.82B 84.88M 576M 225M 2.92B 228M 223M 9.67B 129M 111M 104M 94.78M 178M 12.36B 180M 1.22B 477M 6.21B 485M 475M 20.54B
Net income -452M -387M -362M -332M -622M -43.25B -631M -4.28B -1.67B -21.73B -1.7B -1.66B -71.86B -453M -388M -363M -332M -624M -43.36B -632M -4.29B -1.67B -21.78B -1.7B -1.66B -72.04B
Net Debt -708M -607M -568M -520M -975M -67.78B -988M -6.71B -2.62B -34.05B -2.66B -2.6B -113B -749M -641M -600M -549M -1.03B -71.63B -1.04B -7.09B -2.76B -35.98B -2.81B -2.75B -119B
Logo Denali Therapeutics Inc.
Denali Therapeutics Inc. is a biopharmaceutical company establishing a new class of biotherapeutics designed to cross the blood-brain barrier using its TransportVehicle platform. It is focused on building a portfolio of therapeutic candidates by investing in its TV franchises, i.e., Enzyme TV (ETV), Oligonucleotide TV (OTV), and Antibody TV (ATV), to advance programs for rare diseases, such as lysosomal storage diseases, and common diseases, such as Alzheimer's disease and Parkinson's disease. Its most advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (Hunter syndrome). TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for mucopolysaccharidosis IIIA (Sanfilippo syndrome type A), DNL593 (PTV:PGRN) for frontotemporal dementia-granulin, DNL628 (OTV:MAPT) for Alzheimer’s disease, and DNL952 (ETV:GAA) for Pompe disease. It is also pursuing opportunities in other disease areas including oncology.
Employees
503
Date Price Change Volume
26-08-21 US$24.92 -0.12% 680,935
26-08-20 US$24.95 -2.88% 976,848
26-08-19 US$25.69 +5.68% 1,150,287
26-08-18 US$24.31 -0.16% 1,099,616
26-08-17 US$24.35 -0.20% 1,003,238
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
20
Last Close Price
24.92USD
Average target price
35.44USD
Spread / Average Target
+42.21%

Quarterly revenue - Rate of surprise

  1. Stock Market
  2. Stocks
  3. DNLI Stock