Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangement of Certain Officers.

Appointment of Chief Financial Officer



Effective January 14, 2022, the board of directors (the "Board") of Exicure,
Inc. (the "Company") promoted Elias D. Papadimas, the Company's current Chief
Accounting Officer, to the role of Chief Financial Officer of the Company,
effective January 17, 2022 (the "Effective Date"), and designated Mr. Papadimas
as the principal financial officer and principal accounting officer of the
Company. Brian C. Bock, the Company's Chief Executive Officer remains the
principal executive officer of the Company. Mr. Papadimas was also appointed as
the corporate secretary of the Company.

Mr. Papadimas joined the Company in April 2015 and has held various positions of
increasing responsibility with the Company including most recently holding the
position of Chief Accounting Officer. Prior to joining the Company, Mr.
Papadimas served as senior manager, technical accounting and external reporting
at Beam Suntory from July 2011 to August 2014. Prior to that, Mr. Papadimas held
various positions in financial reporting, technical accounting and accounting
operations with Aon Hewitt from September 2004 to July 2011, Nicor Gas from
February 2003 to September 2004, and Heller Financial, Inc. from June 1997 to
July 2002. Mr. Papadimas received his B.S. in accountancy from the University of
Illinois at Urbana-Champaign and is a certified public accountant (CPA) in
Illinois.

Mr. Papadimas does not have a family relationship with any director or executive
officer of the Company or person nominated or chosen by the Company to become a
director or executive officer, and there are no arrangements or understandings
between Mr. Papadimas and any other person pursuant to which Mr. Papadimas was
selected to serve as the Chief Financial Officer of the Company. There have been
no transactions involving Mr. Papadimas that would require disclosure under Item
404(a) of Regulation S-K under the Securities Exchange Act of 1934, as amended,
or the Exchange Act.

Employment Arrangements

In connection with Mr. Papadimas' appointment, the Company and Mr. Papadimas
entered into a First Amendment to the Amended and Restated Employment Agreement
(the "Amendment") dated and effective as of the Effective Date, which amends the
Amended and Restated Employment, dated as of June 1, 2021, originally entered by
and between the Company and Mr. Papadimas (the "Employment Agreement"). Pursuant
to the Amendment, Mr. Papadimas' annual base salary was increased from $300,000
to $405,000 in connection with his promotion, and his target bonus percentage
under the Company's annual cash incentive bonus program was increased from 30%
to 40% of his annual base salary. The payment of bonus award, if any, is in the
sole discretion of the Compensation Committee of the Board and is subject to the
attainment of certain Company performance goals set annually by the Compensation
Committee of the Board. Mr. Papadimas' Employment Agreement, as amended by the
Amendment, does not provide for a specified term of employment and Mr.
Papadimas' employment is on an at-will basis. Mr. Papadimas continues to remain
eligible to participate in the Company's employee benefit, welfare and other
plans, as may maintained by the Company from time to time. Mr. Papadimas is also
subject to certain customary confidentiality, non-solicitation and
non-competition provisions.

Pursuant to the Amendment, Mr. Papadimas will also be eligible to receive a
special bonus of $20,000, subject to his continued employment with the Company
through March 15, 2022, payable no later than the next regular payroll following
March 15, 2022.

The foregoing descriptions of the Employment Agreement and the Amendment are not
complete and are qualified in their entireties by reference to the full texts of
the Employment Agreement and the Amendment, copies of which are filed herewith
as Exhibit 10.1 and Exhibit 10.2, respectively, and are incorporated by
reference herein.


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Item 9.01 Financial Statements and Exhibits.


                                                                                            Incorporated by Reference
    Exhibit
      No.                   Exhibit Description                 Form                  Exhibit No.               Filing Date             File No.

10.1                     Amended and Restated
                       Employment Agreement between
                       Exicure, Inc. and Elias D.               10-Q                     10.3                     8/12/21               001-39011
                       Papadimas, dated June 1,
                       2021.

10.2*                    First Amendment to Amended
                       and Restated Employment
                       Agreement between     Exicure,
                       Inc.     and Elias D.
                       Papadimas, dated January 17,
                       2022.

104                    Cover Page Interactive Data
                       File (embedded within the
                       Inline XBRL document).



* Filed herewith

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