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About Vernal Keratoconjunctivitis
Vernal keratoconjunctivitis (VKC) is a rare and potentially debilitating ocular allergic disease.1 Vernal keratoconjunctivitis is characterized by allergic inflammation of the ocular surface, with clinical manifestations involving the tarsal (palpebral) and/or bulbar conjunctiva that can have a seasonal course, but also may be chronic with acute exacerbations.2 Key signs and symptoms of VKC include photophobia, conjunctival hyperemia, itching, stringy mucous discharge, giant papillae on the upper tarsal conjunctiva, papillae and gelatinous infiltrates on the limbus with white-yellow nodules (Horner-Trantas dots), superficial punctate keratitis, and corneal shield ulcers.2-4
About VerkaziaTM
VerkaziaTM cyclosporine 0.1% topical ophthalmic emulsion indicated for treatment of severe vernal keratoconjunctivitis in children from 4 years of age through adolescence.
About Santen
As a specialized company dedicated to ophthalmology, Santen carries out research, development, marketing, and sales of pharmaceuticals, over-the-counter products, and medical devices. Santen is the market leader for prescription ophthalmic pharmaceuticals in
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E-mail: Carol.Stiff@santen.com
Tel: +1-416-918-7751
1 Brémond-Gignac D, Donadieu J, Leonardi A, et al. Prevalence of vernal keratoconjunctivitis: a rare disease Br
2 Leonardi A. Management of vernal keratoconjunctivitis. Ophthalmol Ther. 2013;2:73e88
3 Aragona P, Romeo GF, Puzzolo D, et al. Impression cytology of the conjunctival epithelium in patients with vernal conjunctivitis. Eye (Lond). 1996;10:82e85.
4 Vichyanond P, Pacharn P, Pleyer U, Leonardi A. Vernal keratoconjunctivitis: a severe allergic eye disease with remodeling changes. Pediatr Allergy Immunol. 2014;25:314-322
SOURCE Santen
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