TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES                                                      
                                                                                                        
    1. Identity of the issuer or the underlying issuer of     Manchester & London Investment Trust plc  
    existing shares to which voting rights are attached:                                                
                                                                                                        
    2 Reason for the notification (please tick the appropriate box or boxes):                           
                                                                                                        
    An acquisition or disposal of voting rights                                                  yes    
                                                                                                        
    An acquisition or disposal of qualifying financial instruments which may result                     
    in the acquisition of shares already issued to which voting rights are attached                     
                                                                                                        
    An acquisition or disposal of instruments with similar economic effect to                           
    qualifying financial instruments                                                                    
                                                                                                        
    An event changing the breakdown of voting rights                                                    
                                                                                                        
    Other (please                                                                                       
    specify):                                                                                           
                                                                                                        
    3. Full name of person(s) subject to the                     1607 Capital Partners, LLC             
    notification obligation:                                                                            
                                                                                                        
    4. Full name of shareholder(s)                  Northern      537,737                               
    (if different from 3.):                         Trust                                               
                                                                                                        
                                                    Bny Mellon    382,660                               
                                                                                                        
                                                    State Street  132,000                               
                                                                                                        
                                                                                                        
    5. Date of the transaction and date on which                      January 10, 2017                  
    the threshold is crossed or reached:                                                                
                                                                                                        
    6. Date on which issuer notified:                                 January 12, 2017                  
                                                                                                        
    7. Threshold(s) that is/are crossed or reached:                          5%                         
                                                                                                        

       

    8. Notified details:                                                                                 
                                                                                                         
    A: Voting rights attached to shares                                                                  
                                                                                                         
    Class/type of    Situation previous to the Resulting situation after the triggering transaction      
    shares           triggering transaction                                                              
                                                                                                         
    if possible      Number of    Number of    Number of   Number of voting      % of voting rights x    
    using the ISIN   Shares       Voting       shares      rights                                        
    CODE                          Rights                                                                 
                                               Direct      Direct xi Indirect    Direct       Indirect   
                                                                     xii                                 
                                                                                                         
      GB0002258472    1,077,397    1,077,397                          1,052,397                  4.89%   
                                                                                                         
    B: Qualifying Financial Instruments                                                                  
                                                                                                         
    Resulting situation after the triggering transaction                                                 
                                                                                                         
    Type of financial       Expiration Exercise/ Conversion    Number of voting rights % of voting rights
    instrument              date       Period                  that may be acquired if                   
                                                               the instrument is                         
                                                               exercised/ converted.                     
                                                                                                         
    C: Financial Instruments with similar economic effect to Qualifying Financial                        
    Instruments                                                                                          
                                                                                                         
    Resulting situation after the triggering transaction                                                 
                                                                                                         
    Type of financial  Exercise   Expiration Exercise/     Number of voting rights  % of voting rights   
    instrument         price      date       Conversion    instrument refers to                          
                                             period                                                      
                                                                                                         
                                                                                    Nominal      Delta   
                                                                                                         
    Total (A+B+C)                                                                                        
                                                                                                         
    Number of voting rights                          Percentage of voting rights                         
                                                                                                         
    Same as A                                                                                            
                                                                                                         

       

    9. Chain of controlled undertakings through which the voting rights and/or the              
    financial instruments are effectively held, if applicable:                                  
                                                                                                
    Proxy Voting:                                                                               
                                                                                                
    10. Name of the proxy holder:                                                               
                                                                                                
    11. Number of voting rights proxy holder will cease to                                      
    hold:                                                                                       
                                                                                                
    12. Date on which proxy holder will cease to hold voting                                    
    rights:                                                                                     
                                                                                                
                                                                                                
    13. Additional information:                                                                 
                                                                                                
    14. Contact name:                            Bryan Huntley, CCO                             
                                                                                                
    15. Contact telephone number:                 804-525-1741