Dextech Medical AB announced the upcoming multiple myeloma study. The application for an Fas1 study regarding the effect of OsteoDex on patients with multiple myeloma (MM) was approved and granted permission by the Medical Products Agency on August 10, 2022. The study will include 20 patients and be conducted at 4-5 hospitals in Sweden and other Nordic countries.

Studyn is expected to start in First Quarter 2023 and be completed during fourth quarter, 2024.  Principal investigator (PI) is Dr. Katarina Uttervall, MD, PhD, Division of Hematology/HERM, Karolinska University Hospital, Huddinge. The main blood markers will be analyzed at the Central Laboratory, Karolinska University Hospital, NKS, Solna.

The study duration for each individual patient is 14 weeks, from screening to follow-up visits. Each patient will receive OsteoDex every two weeks, a maximum of 7 doses. Adult MM patients with recurrent/treatment-resistant disease, who received 1-3 previous lines of therapy, will be included.

The primary objective is to confirm safety and tolerability. The secondary objective is to determine treatmentresponse, change in the level of disease-related biomarkers, and documentation of quality of life (QoL scores).