On December 31, 2017, Werner Cautreels notified Selecta Biosciences, Inc. of his planned retirement as the company's President and Chief Executive Officer, to be effective December 31, 2018. In connection with Dr. Cautreels anticipated retirement, Omid Farokhzad, M.D., has been appointed to serve as the Chairman of the Board of Directors of the company, effective December 31, 2017.