You should read the following discussion of our financial condition and results of operations in conjunction with the condensed consolidated financial statements and the related notes included elsewhere in this Form 10-Q and with our audited consolidated financial statements included in our Annual Report on Form 10-K for the year endedDecember 31, 2021 , as filed with theSEC onApril 18, 2022 . In addition to our historical condensed consolidated financial information, the following contains forward-looking statements that reflect our plans, estimates, and beliefs. Our actual results could differ materially from those discussed in the forward-looking statements. Factors that could cause or contribute to these differences include those discussed below and elsewhere
in this Form 10-Q. Overview We operate a life sciences company focused on improving outcomes for patients with cancer. Our plan is to develop and commercialize a variety of products in the diagnostics, pharmaceutical and medical device spaces that enable more informed treatment planning and more effective treatment options for patients. Our initial approach will be the commercialization of a proprietary genomic platform, StemPrint, for recurrence risk stratification of different types of cancer. To augment this unique offering we also plan to provide ancillary commodity testing (e.g., hereditary genetic testing, somatic mutation testing) to provide additional information and value to our clients.StemPrintER Sciences Limited "StemPrintER" was transferred to theAccuStem Sciences Limited onOctober 30, 2020 pursuant to the demerger of the StemPrintER and SPARE projects from Tiziana. The objective of the demerger was to maximize value to the shareholders of Tiziana through the further commercialization of the StemPrintER project and its assets and intellectual property. The Demerger will allow us to continue its collaboration strategy to further develop, validate and commercialize the StemPrintER/SPARE platform as a separate listed company.
Since our inception, we have devoted substantially all of our resources to conducting research and development of our product candidate. Our revenue is expected to be derived from different sources including standard private third-party and government medical insurance coverage and reimbursement models.
We expect our expenses to increase substantially in connection with our ongoing development activities related to our preclinical and clinical programs. We intend to conduct further validation and utility studies with the intention of filing for regulatory review under the CLIA system and, ultimately, for reimbursement review. We also may pursue a strategy to achieve appropriate regulatory review with European and Asian regulatory agencies to expand the addressable market for its products.
We expect to incur additional costs associated with the expansion of our
management team and operating as a public company in
? build out corporate headquarters and a CLIA-certified laboratory in
AZ; ? continue our research and development efforts; ? seek regulatory approvals for any product candidates that successfully complete clinical trials; and
? add clinical, scientific, operational financial and management information
systems and personnel, including personnel to support our product development
and potential future commercialization claims. 18
As a result, we may need substantial additional funding to support our continuing operations and pursue our growth strategy. Until such time as we can generate significant revenue from product sales, if ever, we expect to finance our operations through a combination of public or private equity or debt financings or other sources, which may include collaborations with third parties. We may be unable to raise additional funds or enter into such other agreements or arrangements when needed on favorable terms, or at all. If we fail to raise capital or enter into such agreements as, and when needed, we may have to significantly delay, scale back or discontinue the development and commercialization of our product candidates. Recent Developments OnMarch 30, 2022 , we completed a common stock capital transaction with Tiziana Life Sciences Ltd. ("Tiziana") pursuant to which Tiziana, purchased 1,337,970 shares of the Company's common stock (the "Common Stock") at a purchase price of$2.00 per share for gross proceeds of$2,675,940 . The purchase of the Common Stock was in accordance with the Supplemental Demerger Agreement datedOctober 5, 2021 between Tiziana and the Company whereby Tiziana agreed to purchase £2,000,000 of shares of the Company's common stock at the time of listing
of the common stock. Management Team Update
On
Impact of the COVID-19 Pandemic
In early 2020, an outbreak of the novel strain of coronavirus (COVID-19) emerged globally. As a result, there have been mandates from federal, state and local authorities resulting in an overall decline in economic activity. There have been no material impacts from COVID-19 on the Company's operations for the periods throughMarch 31, 2022 . However, it is possible that the pandemic will continue to significantly impact economies worldwide, which could result in adverse effects on the Company's operations. The extent of the impact of COVID-19 on operations, liquidity, financial condition, and results of operations remain uncertain at this time.
Financial Operations Overview
We have no products approved for commercial sale and have not generated revenue to date. We have never been profitable and have incurred net losses in each year since inception. We incurred net losses of$790,534 and$13,873 for the three months endedMarch 31, 2022 and the three months endedMarch 31, 2021 , respectively. As ofMarch 31, 2022 , we had an accumulated deficit of$1,515,396 . Substantially all of our net losses resulted from expenses incurred in connection with our research and development programs and from general and administrative costs associated with our operations. 19 Segment Information
As ofMarch 31, 2022 , we viewed our operations and managed our business as one operating segment consistent with how our chief operating decision maker, our Chief Executive Officer, makes decisions regarding resource allocation and assessing performance. As ofMarch 31, 2022 , substantially all of our assets were located inthe United States . Our headquarters and operations are located inNew York, NY andLondon, UK . Results of Operations
The following discussion and analysis of our results of operations includes a comparison of the three months endedMarch 31, 2022 to the three months endedMarch 31, 2021 : Three Months Ended March 31, 2022 2021 $ Change % Change Revenue $ - $ - $ - - % Research and development expenses 21,143 2,650 18,493 698 % General and administrative expenses 769,391 11,223 758,168 6775 % Loss from operations 790,534 13,873 776,661 5598 % Loss, before income tax (790,534 ) (13,873 ) (776,661 ) 5598 % Income tax benefit (expense) - - - - % Net loss$ (790,534 ) $ (13,873 ) $ (776,661 ) 5598 % Research and development
Research and development expenses increased
General and administrative
General and administrative expenses increased$758,168 in the three months endedMarch 31, 2022 as compared to the three months endedMarch 31, 2021 . The increase was primarily related to an increase of payroll related costs as a result of the new management team structure, as well as costs related to legal fees and other compliance expenses.
Liquidity and Capital Resources
Sources of Liquidity Since our inception, we have not generated any revenue and have incurred significant operating losses. Our potential products are at various phases of development. We do not expect to generate significant revenue from product sales for several years, if at all. Pursuant to the demerger, Tiziana transferred$1,353,373 (£1,000,000) in cash inJanuary 2022 to the Company. In addition, subject to the terms of the supplemental demerger agreement, Tiziana invested$2,675,940 (£2,000,000) in cash inMarch 2022 for additional shares of the Company. Our cash flows may fluctuate and are difficult to forecast and will depend on many factors. As ofMarch 31, 2022 , our cash balance is$3,244,600 , which is adequate for our current planned level of operations, through at leastNovember 2022 . 20
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