PRESS RELEASE Proteome Sciences plc ("Proteome Sciences" or the "Company") Director's Shareholding

The Company has been informed that Roger McDowell, Non-Executive Director, today purchased 500,000 ordinary shares of 1p each a price of 37.474 pence per share. Following this transaction, Mr. McDowell holds in 500,000 ordinary shares in Proteome Sciences, representing approximately 0.23 per cent. of the Company's issued share capital.
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For further information please contact: Proteome Sciences plc

Christopher Pearce, Executive Chairman
Dr. Ian Pike, Chief Operating Officer
James Malthouse, Finance Director
Tel: +44 (0)1932 865065

Nominated Adviser Cenkos

Stephen Keys/Callum Davidson Tel: +44 (0)20 7397 8900

Public Relations IKON Associates Adrian Shaw

Tel: +44 (0)1483 271291

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