Plant Health Care plc announced 2012 trial results which once again demonstrated that its Harpin seed treatment delivers substantial yield increases when combined with industry standard seed treatments in corn, soybeans and wheat, the United States' three largest-area field crops. Soybean treated with Harpin in addition to other market products produced an additional two bushels per acre. This is equivalent to an uplift in yield of approximately 3.5%, worth $25 per acre at current market prices.

This indicates an 8:1 return on US farmers' investment in Harpin. In corn, the use of Harpin increased yields over base insecticide and fungicide treatments by 18.6 bushels per acre, offering potential incremental revenue of $111 per acre. In wheat, the use of Harpin added 2.8 bushels per acre in average yield beyond that achieved from a treatment consisting of only insecticide and fungicide.

This would equate to additional revenue of $23 per acre. Field trials were conducted as part of Direct Enterprise Inc.'s (DEI's) annual comprehensive seed treatment study and involved evaluation by independent contract researchers across 14 states using the Random Complete Block design, with three replications per treatment at each location.