Item 5.07. Submission of Matters to a Vote of Security Holders. The 2021 Annual Meeting of Stockholders of the Company (the "Annual Meeting") was held on May 19, 2021. As of the close of business on March 23, 2021, the record date for the Annual Meeting, there were 94,535,739 shares of common stock entitled to vote, of which there were 85,244,517 shares present at the Annual Meeting in person or by proxy. At the Annual Meeting, stockholders voted on three matters: (i) the election of three Class I Directors for a term of three years expiring at the 2024 Annual Meeting of Stockholders, (ii) an advisory vote on the compensation paid to the Company's named executive officers, and (iii) the ratification of the appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2021. The voting results were as follows: • Election of three Class I Directors for a term of three years expiring at the 2024 Annual Meeting of Stockholders. William H. Rastetter, Ph.D. For 70,689,819 Withheld 9,590,937 George J. Morrow

                For   75,617,578      Withheld   4,663,178
Leslie V. Norwalk               For   63,595,461      Withheld  16,685,295


There were 4,963,761 broker non-votes for this proposal. The three nominees for Class I Director were elected. The Class II Directors, Richard F. Pops, Shalini Sharp and Stephen A. Sherwin, M.D., will continue in office until the 2022 Annual Meeting of Stockholders or until their earlier death, resignation or removal. The Class III Directors, Kevin C. Gorman, Ph.D., Gary A. Lyons and Johanna Mercier will continue in office until the 2023 Annual Meeting of Stockholders, or until their earlier death, resignation or removal. • An advisory vote on the compensation paid to the Company's named executive officers. Shares Voted: For 77,232,378 Against 2,952,915 Abstain 95,463 Percent of Voted: For 96.20 % Against 3.67 %

There were 4,963,761 broker non-votes for this proposal. The compensation of the Company's named executive officers, as disclosed in the Proxy Statement, was approved on an advisory basis. •Ratification of the appointment of Ernst & Young LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2021.



Shares Voted:         For   82,408,785     Against   2,768,444     Abstain   67,288
Percent of Voted:     For     96.67  %     Against     3.24  %


The appointment of Ernst & Young LLP was ratified.

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