Jaguar Health, Inc. provided updates regarding the Company’s plans to explore the possibility of obtaining conditional marketing authorization in Europe to support development and commercialization of crofelemer, the Company’s novel proprietary drug, for the proposed indication of prophylaxis and/or symptomatic relief of inflammatory diarrhea, initially to be studied in a “long-hauler” COVID-19 recovery patient population in Europe. As part of the Company’s investigation into the feasibility of the conditional marketing authorization pathway, which provides a fast-track clinical review process during public health emergencies, the Company plans to request meetings with the European Medicines Agency (EMA), Swissmedic, and the Medicines and Healthcare products Regulatory Agency (MHRA) of the United Kingdom. The EMA, in particular, has established regulatory approval schemes for COVID-19-related treatments. The head of emergencies at the World Health Organization stated on October 5, 2020 that the agency’s “best estimates” indicate that roughly 1 in 10 people worldwide may have been infected by COVID-19 – more than 20 times the number of confirmed cases. According to the New York Times, the new, more contagious strain of COVID-19 has now been detected in 45 countries. Imperial College London estimates that the new strain tripled its number of infections in England during the November 2020 lockdown.