The MEDITWIN project will offer personalized virtual twins of organs, metabolism and cancer, for better diagnosis and treatment. In particular, MEDITWIN will enable doctors to simulate future scenarios for a patient.
Seven new medical practices will be developed from the virtual twins, in neurology, cardiology and oncology. This will result in seven "virtual healthcare products" that will be deployed on a sovereign industrial cloud platform.
The MEDITWIN project leverages the expertise of world-class partners in each of the fields covered, around the 14 founding members of this consortium:
Virtual twins have become an indispensable asset in the aeronautics and mobility industries, where virtualization has enabled considerable progress in terms of safety, quality, ecological footprint and cost-effectiveness. MEDITWIN builds on the experience accumulated by the partners over many years in the field of virtual twins for healthcare, such as the Living Heart initiative by
MEDITWIN will enable the industrialization, clinical validation and standardization of these innovations, so that these technologies can be deployed in a standardized way and benefit as many people as possible. The best standards of care will be incorporated into virtualized experiences made accessible worldwide, setting a new benchmark for quality in healthcare and providing a decisive learning ground for progress in medical science.
The benefits of virtual twins will be assessed for medical teams, patients, and the healthcare system, notably in terms of improving the efficiency of care, quality of multidisciplinary decision-making, and effectiveness and safety of medical practices and interventions.
In practice, the MEDITWIN initiative will be developed over five years, from 2024 to 2029. The partners' investment in this project will be financially supported by the French government as part of the "
Partner quotes
"Virtual twins have successfully enabled the industrial world to transform itself more sustainably. Today, this technology is opening up new possibilities for healthcare by revealing the secrets of the human body - by understanding and representing the invisible. For 40 years,
Bruno Sportisse, CEO of Inria
"Building an active digital ecosystem can only make
"The MEDITWIN consortium is in line with PRISM's vision of developing cancer avatars to model biology at the patient level and tailor personalized therapies. PRISM will also benefit from the expertise of the other IHUs, and will be working closely with them to develop interdisciplinary projects."
Pierre JAIS, CEO of IHU LIRYC
"Combining 7 IHUs, Inria and
Pr.
"Virtual twins will be essential elements in the medicine of the future, as they will enable treatments to be simulated to provide patients with the best possible results. MEDITWIN is an exceptional project in terms of its ambition and the challenges to be met. It's also a premiere for the IHU France alliance, uniting a multidisciplinary biomedical research capability that has no parallel anywhere in the world. For IHU Strasbourg, it will be a powerful catalyst for improving the minimally invasive management of metastatic colorectal cancer, in close collaboration with two of its historical founders, Inria and the University Hospitals of
Pr. Michel Paques, IHU FOReSIGHT, head of the ophthalmology 4 department and Director of the Clinical Investigation Center at the 15-20 national hospital
"The integration of the FOReSIGHT IHU into the MEDITWIN consortium will enable the large-scale development of retinal microcirculation twins, enabling personalized detection and monitoring of cerebral and cardiovascular diseases in quantitative terms. This will be the first development of a quantitative microcirculatory biomarker. The FOReSIGHT IHU has developed expertise in innovative microvascular imaging using retinal imaging with adaptive optics, a technique in which
Pr. Stanislas Lyonnet, CEO of Institut Imagine
"Institut Imagine is proud to have been one of the initiators of the strategic partnership between
Pr.
"We are delighted to collaborate closely with
Pr.
"Virtual twin technology opens up possibilities for novel precision and preventive medicine for cardiometabolic diseases. Its goal is to predict the personal future risk of developing a cardiovascular disease, based on individual risk profiles, especially the genomic signature. Such an ambition requires changing the scale of today's research that will be achieved through the MEDITWIN project led by
Pr.
"
Todor Jeliaskov, CEO of inHEART
"At inHEART, we are excited to be part of MEDITWIN and on the forefront of the digital health transformation. Within MEDITWIN, inHEART will focus on the prevention of Sudden Cardiac Death, which takes more than 800,000 lives each year. We need to move our healthcare systems from reacting to acute complications to preventing complications. Digital technologies and Artificial Intelligence are accelerating this process."
"The MEDITWIN project has succeeded in bringing together the medical expertise of several different
Stanley Durrleman, CEO of QAIRNEL
"At Qairnel, we're proud to be part of the MEDITWIN project. Our virtual twins simulate the evolution of a patient in the early stages of Alzheimer's disease. The project will enable us to put these technologies into the hands of practitioners, to propose personalized management schemes and therapeutic strategies. This will enable us to respond to one of the major public health challenges of the 21st century."
"Neurometers aims to generalize the medical use of the electroencephalogram (EEG) to quantify the cerebral signatures of consciousness and cognition. Initially developed in healthy subjects and non-communicative patients, with highly original results validated in numerous scientific publications, we have more recently discovered and reported that this approach could prove highly promising in the field of neurodegenerative diseases that impair cognition, such as Alzheimer's disease. For the first time, direct measures of cognitive functioning could be integrated into routine clinical monitoring of patients, complementing neuropsychological tests and measures of cerebral atrophy. This approach could also make it possible to evaluate the efficacy of new therapies. Our participation in the MEDITWIN project is aimed at improving the quality of our algorithms by analyzing a large cohort of patient EEG recordings in an evolutionary manner."
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About
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- Reflects a double ambition: sustainably transform key sectors of our economy (energy, automotive, aeronautics or space) through technological innovation, and position
- Is unpublished by its magnitude:
- Will be implemented collectively: designed and deployed in consultation with economic, academic, local and European stakeholders to determine their strategic orientations and flagship actions. Project leaders are invited to submit their application via open, demanding and selective procedures to benefit from the support of the State.
- Is led by the General Secretariat for Investment on behalf of the Prime Minister and implemented by the
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