Item 8.01. Other Events.

On January 20, 2022, Compass Therapeutics, Inc. (the "Company") issued a press release titled "Compass Therapeutics Announces US FDA Clearance of Investigational New Drug Application for a Phase 2 Study of CTX-009, a bispecific antibody that simultaneously targets Delta-like ligand 4 (DLL4) and vascular endothelial growth factor A (VEGF-A)" A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits

99.1 Press release dated January 20, 2022

104 Cover Page Interactive Data File (embedded within the Inline XBRL document)

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