Castle Biosciences, Inc. announced that Bernhard E. Spiess, former Chief Business Officer of the company, notified the company of his intention to resign effective as of December 31, 2021. On December 29, 2021, in connection with his resignation, the company entered into an Employment Separation Agreement with Spiess. Additionally, the Company entered into a Master Services Agreement with Spiess, pursuant to which Spiess will provide consulting services to the company.