Extraction of Acidic Catecholamine Metabolites in Plasma Using EVOLUTE® EXPRESS ABN Prior to LC-MS/MS Analysis
31 January 2018This application note describes a solid phase extraction protocol for the extraction of three catecholamine metabolites (vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid) from plasma prior to LC-MS/MS detection. The method described in this application delivers high analyte recoveries and excellent linearity in the range 10-200 mg/mL.
EVOLUTE® EXPRESS SPE products dramatically improve flow characteristics, and enhance sample preparation productivity.
- Vanillylmandelic acid (VMA)
- 5-hydroxyindoleacetic acid (5-HIAA)
- Homovanillic acid (HVA)
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Biotage AB published this content on 31 January 2018 and is solely responsible for the information contained herein.
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