The Board of Directors of TG Therapeutics, Inc. has determined that it is in the Company’s best interests to designate a lead independent director. On June 16, 2021, the Board appointed Mr. Laurence Charney as lead independent director. Mr. Michael S. Weiss will continue to serve as Chairman. In connection with the appointment of Mr. Charney as lead independent director, Mr. Weiss’ title was changed from Executive Chairman and Chief Executive Officer to Chairman and Chief Executive Officer. Additionally, on June 18, 2021, effective as of June 30, 2021, Mr. Weiss and the Company agreed to terminate the Strategic Advisory Agreement (the “Advisory Agreement”) with Caribe BioAdvisors, LLC owned by Mr. Weiss to provide the services of Mr. Weiss as Chairman of the Board and as Executive Chairman.