Certain Restricted Stock Units of Strongbridge Biopharma plc are subject to a Lock-Up Agreement Ending on 2-JAN-2018. These Restricted Stock Units will be under lockup for 90 days starting from 4-OCT-2017 to 2-JAN-2018. Details: The officers and directors have agreed that they will not directly or indirectly, offer, pledge, sell, contract to sell, sell any option or contract to purchase, purchase any option or contract to sell, grant any option, right or warrant to purchase or otherwise transfer or dispose of any ordinary shares or any securities underlying, convertible into or exercisable or exchangeable for ordinary shares, for a period of 90 days after the date of the underwriting agreement without the prior written consent of Cantor Fitzgerald & Co.