Starpharma : Notice of initial substantial holder

Form 603 Corporations Act 2001

Section 671B

Notice of Initial Substantial Holder

To: STARPHARMA HOLDINGS LIMITED

ACN/ARSN:

1. Details of substantial holder (1)

Name: FIL Limited and the entities listed in Annexure A ("FIL") ACN/ARSN (if applicable)

The holder became a substantial holder on

09 January 2019

2. Details of voting power

The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in on the date the substantial holder became a substantial holder are as follows:

Class of Securities (4)	Number of securities	Person's votes (5)	Voting power (6)
COMMON STOCK	18,729,813	18,729,813	5.04%

3. Details of relevant interests

The nature of the relevant interest the substantial holder or an associate had in the following voting securities on the date the substantial holder became a substantial holder are as follows:

Refer to Annexure A

4. Details of present registered holders

The persons registered as holders of the securities referred to in paragraph 3 above are as follows:

Refer to Annexure A

5. Consideration

The consideration paid for each relevant interest referred to in paragraph 3 above, and acquired in the four months prior to the day that the substantial holder became a substantial holder is as follows:

Date of Acquisition	Holder of Relevant Interest	Consideration (9)	Class and Number of Securities
AUD	COMMON STOCK
10-Oct-18	FIL	1.5125	127,823
30-Nov-18	FIL	1.5600	183,599
3-Dec-18	FIL	1.5636	22,590
3-Dec-18	FIL	1.5636	38,914
4-Dec-18	FIL	1.5505	22,482
4-Dec-18	FIL	1.5505	38,726
5-Dec-18	FIL	1.4836	26,183
5-Dec-18	FIL	1.4836	45,104
6-Dec-18	FIL	1.4500	167,768
6-Dec-18	FIL	1.4500	288,996
9-Jan-19	FIL	1.1160	110,825
9-Jan-19	FIL	1.1160	61,779
Total Acquisition	1,134,789

6. Associates

The reasons the persons named in paragraph 3 above are associates of the substantial holder are all follows:

Name and ACN/ARSN (if applicable)	Nature of association
N/A

7. Addresses

The addresses of persons named in this form are as follows:

Refer to Annexure A

Sign Here ____________________________________

Dated: 11 January 2019

Jen Li

Head of Regulatory Reporting, Asia Pacific

Duly authorized under Powers of Attorney by and on behalf of FIL Limited

Annexure A

Investment Manager	Address	Custodian	Nature of Relevant Interest	Sum of Numerator Shares
FIL INVESTMENT MANAGEMENT	Level 11, 167 Macquarie Street,	JP MORGAN, BOURNEMOUTH (C)	Investment Discretion /	571,491
(AUSTRALIA) LIMITED	Sydney, NSW 2000,	JPMORGAN CHASE BANK		706,164
Australia	NA LDN
NATIONAL ASTL BK MELBOURNE (S)	172,391
NORTHERN TRUST LONDON (C)	55,669
STATE STREET BANK AND TR CO	344,000
FIL INVESTMENT MANAGEMENT	Level 21, Two Pacific Place, 88 Queensway,	BROWN BROS HARRIMN LTD LUX (C)
			Voting Power	13,931,810
(HONG KONG)	Admiralty, Hong Kong	CLEARSTREAM BANKING	772,709
LIMITED	SA LUX (C)
FIL LIMITED	Pembroke Hall, 42 Crow Lane, Pembroke, Bermuda	HSBC BANK PLC (C)	1,489,643
FIL PENSION MANAGEMENT	Oakhill House, 130 Tonbridge Road, Hildenborough, Kent, England TN119DZ	HSBC BANK PLC (C)	685,936
Grand Total	18,729,813