Item 7.01 Regulation FD Disclosure.

On January 5, 2022, SAB Biotherapeutics, Inc. (the "Company") previously announced that Eddie J. Sullivan, PhD., co-founder, president, and CEO, would present at the H.C. Wainwright BioConnect Virtual Conference held during January 10-13, 2022. Following such announcement, the Company determined that it will not participate in the H.C. Wainwright BioConnect Virtual Conference. As a result, there will be no on-demand webcast of the presentation on the Company's website.

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