Rezolute, Inc. Announces Appointment of Christine Ferrara as Director of Clinical Development
April 09, 2018 at 08:00 am
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Rezolute, Inc. announced that Christine Ferrara, M.D., Ph.D., has joined the company as Director of Clinical Development. In addition to supporting clinical development of the company’s pipeline generally, Dr. Ferrara will have primary responsibility for the clinical development program of RZ358 for Congenital Hyperinsulinemia (CHI), a life-threatening ultra-orphan disease with a substantial unmet need for safer and more effective therapies. Dr. Ferrara joins Rezolute as the company prepares to initiate a Phase 2b study of RZ358. Dr. Ferrara is Assistant Professor of Pediatrics at University of California, San Francisco (UCSF) where she also serves as head of the regional treatment center for patients with CHI. She brings to Rezolute a wealth of experience as a Principal Investigator on industry and government-sponsored clinical trials.
Rezolute, Inc. is a clinical-stage biopharmaceutical company, which is developing therapies for metabolic diseases related to chronic glucose imbalance. The Companyâs lead clinical asset, RZ358, is in late-stage development for the treatment of congenital hyperinsulinism (HI), an ultra-rare pediatric genetic disorder characterized by excessive production of insulin by the pancreas in Phase III. RZ358 is an intravenously administered human monoclonal antibody that binds to a unique site (allosteric) on the insulin receptor in insulin target tissues, such as in the liver, fat and muscle. Its second clinical asset, RZ402, is an oral plasma kallikrein inhibitor (PKI) being developed as a therapy for the chronic treatment of diabetic macular edema (DME) in Phase II. RZ402 is designed to be a once daily oral therapy for the treatment of DME and unlike the anti-VEGF therapies, RZ402 targets the Kallikrein-Kinin System to address inflammation and vascular leakage.