Regulus Therapeutics Inc. announced the appointment of Denis Drygin, Ph.D., as Chief Scientific Officer effective August 3, 2020. Dr. Drygin joins Regulus from Pimera, where he was founder and Vice President of Research and Development since 2013. Prior to Pimera, Denis served with Cylene Pharmaceuticals for over 8 years, most recently as Vice President of Biology where he led the initiation of a Phase I clinical trial for CX-5461, supervising development and translation of predictive and prognostic biomarkers. Prior to this, he led biology operations where he oversaw preclinical development of CX-5461, a first-in-class selective inhibitor of Pol I, and the preclinical development program for Silmitasertib, a first-in-class oral inhibitor of Ser/Thr kinase CK2. Prior to Cylene, Denis completed his post-doctoral work at Ionis Pharmaceuticals, where he served as lead scientist on several projects to investigate the pharmacology and toxicology of antisense oligonucleotides (ASOs).