On April 3, 2017, Provectus Biopharmaceuticals, Inc. announced each of Alfred E. Smith, IV, Timothy C. Scott and Kelly M. McMasters, MD notified the company of their decision to resign from the Board effective immediately. No director’s resignation was due to any disagreement with the Company on any matter relating to the Company’s operations, policies or practices. On April 3, 2017, the Board appointed each of Dominic Rodrigues and Bruce Horowitz to the Board to fill two vacancies. The Board also selected Mr. Rodrigues to serve as chairman of the Board, effective immediately. Each of Messrs. Rodrigues and Horowitz will serve until, and will be nominated for election at, the 2017 Annual Meeting of Stockholders of the company.