PHOTOCURE ASA Press Release -Oslo, Norway ,April 30, 2024 :Photocure ASA (OSE: PHO), theBladder Cancer Company , announces its participation in theAmerican Urological Association Annual Congress (AUA 2024) to be heldMay 3-6, 2024 inSan Antonio, TX , USA. Two AUA program highlights will feature Blue Light Cystoscopy with Cysview[®] study data: · On Sunday, May 5[th], Dr.Sanjay Das will present the study, "Use of Blue Light Cystoscopy Among Non-Muscle Invasive Bladder Cancer Patients and Outcomes in an Equal Access setting: A Propensity Scored Matched Analysis" The study, known as BRAVO (Bladder Cancer Recurrence Analysis in Veterans and Outcomes), is a retrospective, propensity score matched analysis that evaluated oncologic outcomes following BLC[®] compared to WLC alone in patients from theVeterans Affairs (VA) Healthcare System . (PD48: Bladder Cancer: Non-invasive III,Sunday, May 5, 2024 1:00 PM to 3:00 PM , room 304A) · Monday, May 6[th], Poster presentation by Dr.Hailong Hu : "Blue Light Cystoscopy versus White Light Cystoscopy for the Detection of Bladder Cancer using modern HD 4K equipment: An Analysis of Pivotal Trial and Real-World Data". This pooled meta-analysis includes data from a randomized clinical trial and a supporting real-world evidence study conducted inChina . (MP71: Bladder Cancer: Non-invasive IV,Monday, May 6, 2024 9:30 AM to 11:30 AM , room 302B)AUA Congress attendees can meet thePhotocure team on booth number 601 and gain hands-on experience in the blue light cystoscopy with Cysview procedure using the Saphira HD equipment. Note to editors: All trademarks mentioned in this release are protected by law and are registered trademarks ofPhotocure ASA . This press release may contain product details and information which are not valid, or a product is not accessible, in your country. Please be aware thatPhotocure does not take any responsibility for accessing such information which may not comply with any legal process, regulation, registration or usage in the country of your origin. About Bladder Cancer Bladder cancer ranks as the 8[th] most common cancer worldwide - the 5[th] most common in men - with 1 949 000 prevalent cases (5-year prevalence rate)[1a], 614 000 new cases and more than 220 000 deaths in 2022.[1b] Approx. 75% of all bladder cancer cases occur in men.[1] It has a high recurrence rate with up to 61% in year one and up to 78% over five years.[2] Bladder cancer has the highest lifetime treatment costs per patient of all cancers.[3] Bladder cancer is a costly, potentially progressive disease for which patients have to undergo multiple cystoscopies due to the high risk of recurrence. There is an urgent need to improve both the diagnosis and the management of bladder cancer for the benefit of patients and healthcare systems alike. Bladder cancer is classified into two types, non-muscle invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC), depending on the depth of invasion in the bladder wall. NMIBC remains in the inner layer of cells lining the bladder. These cancers are the most common (75%) of all BC cases and include the subtypes Ta, carcinoma in situ (CIS) and T1 lesions. In MIBC the cancer has grown into deeper layers of the bladder wall. These cancers, including subtypes T2, T3 and T4, are more likely to spread and are harder to treat.[4] [1 ]Globocan. a) 5-year prevalence / b) incidence/mortality by population. Available at: https://gco.iarc.fr/today, accessed [February 2024 ]. [2 ]Babjuk M, et al. Eur Urol. 2019; 76(5): 639-657 [3 ]Sievert KD et al. World J Urol 2009;27:295-300 [4 ]Bladder Cancer.American Cancer Society . https://www.cancer.org/cancer/bladder-cancer.html About Hexvix[®]/Cysview[®] (hexaminolevulinate HCl) Hexvix/Cysview is a drug that preferentially accumulates in cancer cells in the bladder, making them glow bright pink during Blue Light Cystoscopy (BLC[®]). BLC with Hexvix/Cysview, compared to standard white light cystoscopy alone, improves the detection of tumors and leads to more complete resection, fewer residual tumors, and better management decisions. Cysview is the tradename in theU.S. andCanada , Hexvix is the tradename in all other markets.Photocure is commercializing Cysview/Hexvix directly in theU.S. andEurope and has strategic partnerships for the commercialization of Hexvix/Cysview inChina ,Chile ,Australia ,New Zealand andIsrael . Please refer to https://photocure.com/partners/our-partners for further information on our commercial partners. AboutPhotocure ASA Photocure :The Bladder Cancer Company delivers transformative solutions to improve the lives of bladder cancer patients. Our unique technology, making cancer cells glow bright pink, has led to better health outcomes for patients worldwide.Photocure is headquartered inOslo, Norway and listed on theOslo Stock Exchange (OSE: PHO). For more information, please visit us at www.photocure.com, www.hexvix.com, www.cysview.com For further information, please contact:Dan Schneider President and CEOPhotocure ASA Email: ds@photocure.comErik Dahl CFOPhotocure ASA Tel: +4745055000 Email: ed@photocure.comDavid Moskowitz Vice President, Investor RelationsPhotocure ASA Tel: +1 202 280 0888 Email: david.moskowitz@photocure.com Media and IR enquiries: Geir Bjørlo Corporate Communications (Norway ) Tel: +47 91540000 Email: geir.bjorlo@corpcom.no
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