Otonomy, Inc. announced positive results from its pivotal Phase 3 clinical trial of OTIPRIO (ciprofloxacin otic suspension) in patients with acute otitis externa (AOE), also known as swimmer's ear. This single administration trial of OTIPRIO met the primary endpoint by showing a statistically significant increase in clinical cure rate compared to sham (no treatment) at Day 8 (p<0.001). Treatment with OTIPRIO was also well tolerated. Based on these positive results, Otonomy expects to submit a supplemental New Drug Application (sNDA) with the U.S. Food and Drug Administration (FDA) in the first half of 2017.