An article entitled 'Living Longer and Better' highlighted research from
A major challenge in Alzheimer's research has been how to find senescent cells in a tissue because they comprise only about 2% of cells, and their complex molecular signature differs across tissues.
The CosMx SMI is the only instrument that has provided us with the opportunity to simultaneously visualize more than one thousand genes, at subcellular resolution, and across all cells in a tissue,' said
CosMx SMI enables high-resolution imaging of more than 1,000 RNA and over 64 protein analytes within morphologically intact whole tissue sections. The CosMx instrument allows researchers to visualize and quantify gene and protein expression at single cell and subcellular resolutions within both fresh frozen and formalin-fixed paraffin-embedded (FFPE) tissue samples. Using a multi-modality approach, including protein imaging, CosMx SMI delivers best-in-class cell segmentation. With high-plex in situ analysis, researchers can perform cell typing, cell state, functional, and cell-cell interaction analyses in a single experiment to generate high-resolution cell atlases.
The CosMx SMI is the newest product in the company's industry-leading spatial analysis portfolio, joining the GeoMx Digital Spatial Profiler (DSP). The GeoMx DSP is a fully-automated spatial profiler allowing multi-cellular analysis of whole transcriptome for both human and mouse applications. Both platforms are also customizable for other species.
About
The GeoMx Digital Spatial Profiler, cited in approximately 190 peer-reviewed publications, is a flexible and consistent solution combining the power of whole tissue imaging with gene expression and protein data for spatial whole transcriptomics and proteomics from one FFPE slide. The CosMx Spatial Molecular Imager is an FFPE-compatible, single-cell imaging platform powered by spatial multiomics enabling researchers to map single cells in their native environments to extract deep biological insights and novel discoveries from one experiment. The AtoMx Spatial Informatics Platform is a cloud-based informatics solution with advanced analytics and global collaboration capabilities, enabling powerful spatial biology insights anytime, anywhere. At the foundation of our research tools is our nCounter Analysis System, cited in more than 6,500 peer-reviewed publications, which offers a secure way to easily profile the expression of hundreds of genes, proteins, miRNAs, or copy number variations, simultaneously with high sensitivity and precision.
Contact:
Tel: 206-602-1768
Email: dfarrell@nanostring.com
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