IsoPlexis announced a partnership with MediMergent, LLC, and The Center for Cancer and Blood Disorders (CCBD), an American Oncology Partners of Maryland practice, to leverage IsoPlexis' single-cell proteomics in a large multi-site study of immuno-compromised cancer patients. The study entitled "Real World Evaluation of the Effectiveness of AZD7442 for Prevention of COVID-19 Infection in Immuno-Suppressed Cancer Patients", will focus on immune cells' functionality and their role in prevention of COVID-19 breakthrough infections in immuno-compromised patients, following administration of AZD7442 IM or IV. IsoPlexis' platform uniquely reveals highly active cells capable of secreting multiple cytokines simultaneously.

The company's single-cell proteomics technology enables researchers to identify these highly powerful single cells which correlate with immune response, therapeutic persistence, and disease outcomes. In partnership with MediMergent, which designs and deploys programs to collect Real-World Evidence used for regulatory submission and product commercialization, and CCBD, a leading community oncology practice with locations in Bethesda and Germantown, Maryland, IsoPlexis will enable researchers to uncover T cell activity and mechanisms associated with COVID-19 breakthrough infections in immuno-compromised cancer patients.