Integrum and Onkos Surgical have entered into a multi-year collaboration focused on the US market. Integrum's OPRA™ Implant System is an innovative technology aimed at helping improve the quality of life for amputees. Together Integrum and Onkos Surgical aim to increase adoption for bone-anchored prosthetic technology in key US surgical centers. Onkos Surgical was musculoskeletal oncologists and The OPRA™ Implant System consists of an anchorage element the patients they (fixture) and a skin penetrating device (abutment). The care for. Built prosthetic leg is then attached directly to the abutment on a digital via the OPRAT™ AXOR™, a prosthetic connection and safety platform, Onkos is device in the field of personalized orthopaedics. With expertise in personalized surgical planning, 3D modeling and the latest advancements in 3D printing, the company has developed a suite of products designed to reduce complexity and address the clinical challenges associated with tumor and complex orthopedic revision surgery. Integrum's OPRA™ (Osseoanchored Prostheses for the Rehabilitation of Amputees) Implant System is the only FDA-approved, bone-anchored prosthetic solution available in the United States. OPRA™ consists of an anchorage element (fixture) and a skin penetrating device (abutment). The fixture is surgically inserted into the femur and after a healing time of several months the abutment is connected to the fixture. The prosthetic leg is then attached directly to the abutment via the OPRA™ Axor™, a prosthetic connection and safety device.