eSense-Lab Ltd. provided the following update with regards to the research conducted on its proprietary terpene profiles being undertaken at the Central Virology Lab of the Ministry of Health. The intention behind this research was to confirm whether the addition of terpenes in sanitisers could mean a reduction of harmful effects on skin, without compromising effectiveness. The commercial goal is to develop a superior organic dominant sanitiser product that provides added protection against bacteria and viruses, while reducing the ethanol content (which is known for its harmful side effects to the skin and its flammability risks). The Company has tested its proprietary terpene formulas with promising results of terpenes' anti- viral synergistic effects. Focus has been on testing two terpene profiles, TRP-ENV and TRP-COV, for their anti-viral activity against HCoV-OC43 Corona strain virus in a range of formulas. Results found more effective anti-viral activity in the TRP-ENV profile, than in the TRP-COV profile. Methodology and Results: HCoV-OC43 viruses were incubated in the presence of the tested items for a period of 1, 3, 10 and 30 minutes. The incubated viruses were then diluted 1:100 and resuspended in the medium of the targeted cells at a final concentration of 0.001MOI (1 virus for every 1000 cells) for infection. Absorption of HCoV-OC43 to the cells was carried out at 33ºC for 1 hour. HCoV-OC43 was then replaced with fresh medium and the cells were incubated for 6 days at 33ºC to allow the virus to replicate, reproduce, and spread out. After 6 days the supernatant of the cells was collected, extracted for viral genetic material and quantified for viral copy number using Real Time PCR.