Cyclacel Pharmaceuticals, Inc. Resignation of Sir John Banham from His Position as A Member of the Board of Directors
September 09, 2020 at 04:32 pm
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On September 2, 2020, Sir John Banham resigned from his position as a member of the board of directors of Cyclacel Pharmaceuticals, Inc. and as a member of all committees of the Board on which he serves. A new chair of the Board's Audit Committee shall be designated.
Cyclacel Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing cancer medicines based on cell cycle, transcriptional regulation and mitosis control biology. The transcriptional regulation program is evaluating fadraciclib, a Cyclin-dependent kinase 9 (CDK9) inhibitor, in solid tumors and hematological malignancies. The epigenetic/anti-mitotic program is evaluating plogosertib, in solid tumors and hematological malignancies. The Company's Plogosertib is a novel, small molecule, selective and potent Polo-like kinase 1 (PLK1) inhibitor, which has demonstrated potent and selective target inhibition (PLK1 IC50 approximately 3 nM) and efficacy in human tumor xenografts at non-toxic doses. Its translational biology program supports the development of plogosertib in solid tumor and hematological malignancy indications.