Item 1.01 Entry into a Material Definitive Agreement.

On January 8, 2023, CinCor Pharma, Inc., a Delaware corporation (the "Company" or "CinCor"), entered into an Agreement and Plan of Merger (the "Merger Agreement"), by and among the Company, AstraZeneca Finance and Holdings Inc., a Delaware corporation ("Parent"), and Cinnamon Acquisition, Inc., a Delaware corporation and a wholly owned subsidiary of Parent ("Purchaser").

Pursuant to the Merger Agreement, and upon the terms and subject to the conditions thereof, Parent has agreed to cause Purchaser to commence a tender offer (the "Offer") no later than January 23, 2023, to acquire all of the outstanding shares of common stock of the Company, par value $0.00001 per share (the "Shares"), at a price of (i) $26.00 per Share (the "Closing Amount"), in cash, plus (ii) one contingent value right (each, a "CVR") per Share representing the right to receive a contingent payment of $10.00 per Share, in cash (the "Milestone Payment") upon the achievement of the milestone set forth in, and subject to and in accordance with the terms and conditions of, a Contingent Value Right Agreement substantially in the form attached as Exhibit E to the Merger Agreement (the "CVR Agreement") as further described below under the heading "-CVR Agreement" (the Closing Amount plus one CVR collectively, the "Offer Price"), in each case, without interest, subject to any applicable withholding taxes.

The obligation of Purchaser to promptly irrevocably accept for payment, and promptly thereafter pay for, all Shares validly tendered (and not validly withdrawn) pursuant to the Offer is subject to satisfaction or waiver of certain conditions set forth in the Merger Agreement, including (i) there being validly tendered and not validly withdrawn Shares that, considered together with all other Shares (if any) beneficially owned by Parent or any of its wholly owned subsidiaries (but excluding Shares tendered pursuant to guaranteed delivery procedures that have not yet been received, as defined by Section 251(h)(6) of the General Corporation Law of the State of Delaware ("DGCL")), represent one more than 50% of the total number of Shares outstanding at the time of the expiration of the Offer and (ii) any waiting period (and any extension thereof) applicable to the Offer under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended, having expired or been earlier terminated. Parent and Purchaser's obligations to consummate the Offer are not subject to a condition that any financing be received by Parent or Purchaser for the consummation of the transactions contemplated by the Merger Agreement.

Following the completion of the Offer and subject to the terms and conditions of the Merger Agreement, Purchaser will be merged with and into the Company (the "Merger") pursuant to Section 251(h) of the DGCL, with the Company continuing as the surviving corporation in the Merger. At the effective time of the Merger (the "Effective Time"), by virtue of the Merger and without any further action on the part of Parent, Purchaser, the Company or any stockholder of the Company, each Share (other than (i) Shares held by the Company (including in the Company's treasury) or any direct or indirect wholly owned subsidiary of the Company, (ii) Shares held by Parent, Purchaser, or any other direct or indirect wholly owned subsidiary of Parent, (iii) Shares irrevocably accepted for purchase in the Offer and (iv) Shares held by stockholders of the Company who have properly exercised and perfected their statutory rights of appraisal under the DGCL) will be converted into the right to receive an amount equal to the Offer Price, without interest and subject to any withholding of applicable taxes.

Each of the Company's stock options (the "Company Options") that is outstanding as of immediately prior to the Effective Time will, except as specified in the Merger Agreement, accelerate and become fully vested and exercisable effective immediately prior to, and contingent upon the occurrence of, the Effective Time. As of the Effective Time:



    (i)  Each vested Company Option with an exercise price less than the Closing
         Amount (an "In-the-Money Option") that is outstanding and unexercised as
         of immediately prior to the Effective Time will be cancelled and
         converted into the right to receive, without interest (a) cash in an
         amount equal to the product of (1) the total number of Shares subject to
         such In-the-Money Option as of immediately prior to the Effective Time
         multiplied by (2) the excess of the Closing Amount over the exercise
         price payable per Share under such In-the-Money Option, and (b) one CVR
         for each Share subject to such In-the-Money Option.



    (ii) Each vested Company Option with an exercise price equal to or greater
         than the Closing Amount (an "Underwater Option") that is then outstanding
         will be cancelled and converted into the right to receive, upon the
         occurrence of the Milestone Payment Date (as defined in the CVR
         Agreement), an amount in cash equal to the product of (a) the total
         number of Shares subject to such Underwater Option immediately prior to
         the Effective Time multiplied by (b) the amount, if any, by which (1) the
         Closing Amount plus the Milestone Payment exceeds (2) the exercise price
         payable per Share under such Underwater Option.

Each of the Company's restricted stock unit awards (the "RSUs") that is outstanding as of immediately prior to the Effective Time will, except as specified in the Merger Agreement, accelerate and become fully vested effective immediately prior to, and contingent upon, the Effective Time. As of the Effective Time, each vested RSU will be canceled and converted into the right to receive, without interest (i) cash in an amount equal to (a) the total number of Shares issuable in settlement of such RSU immediately prior to the Effective Time multiplied by (b) the Closing Amount, and (ii) one CVR for each Share issuable in settlement of such RSU.

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Each Share issued upon early exercise of a Company Option that is subject to vesting, repurchase or other lapse restrictions (a "Restricted Share") that is outstanding as of immediately prior to the Effective Time, will accelerate and become fully vested effective immediately prior to, and contingent upon, the Effective Time. As of the Effective Time, each Restricted Share will be treated as a Share in accordance with the terms of the Merger Agreement and receive the Offer Price.

The holder of each of the Company's warrants (the "Warrants") that is outstanding and unexercised as of immediately prior to the Effective Time, at or following the Effective Time, will be entitled to receive an amount in respect of each Share for which such Warrant is exercisable immediately prior to the Effective Time equal to (i) cash in an amount equal to the product of (a) the total number of Shares subject to such Warrant immediately prior to the Effective Time, multiplied by (b) the excess of (1) the Closing Amount over (2) the exercise price payable per Share under such Warrant, and (ii) one CVR . . .

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

Executive Compensation Arrangements

As described above, in connection with the execution of the Merger Agreement, the Company entered into retention agreements with certain employees of the Company, including executive officer Mason Freeman, setting forth the terms and conditions of continued employment with the Company, as the surviving corporation in the Merger, from and after, and conditioned upon, the consummation of the Merger.

On January 8, 2023, in connection with the approval of the Merger Agreement, the board of directors of the Company approved and authorized that the Company may enter into agreements with each of Catherine Pearce, Marc de Garidel, Mason Freeman and Michael Kalb, which will provide that if such individual is subjected to the excise tax under Section 4999 of the Internal Revenue Code, the Company will reimburse such individual with respect to the payment for the excise taxes (provided that the Company's obligation under these agreements cannot exceed $10.0 million in the aggregate and that such individuals will reasonably cooperate with Parent and the Company to mitigate such excise taxes).

Item 8.01 Other Events.

On January 9, 2023, the Company issued a press release announcing the execution of the Merger Agreement as described above. A copy of the press release is attached as Exhibit 99.1 and incorporated herein by reference.

Additional Information and Where to Find It

The Offer referenced in this filing has not yet commenced. This filing is for information purposes only and is neither an offer to buy nor a solicitation of an offer to sell any securities of the Company, nor is it a substitute for the Offer materials that Purchaser is expected to file with the SEC upon commencement of the Offer. The solicitation of an offer to tender and the offer to buy shares of the Company's common stock will only be made pursuant to a tender offer statement on Schedule TO, including an offer to purchase, a letter of transmittal and other related materials that Purchaser is expected to file with the SEC. In addition, the Company is expected to file with the SEC a Solicitation/Recommendation Statement on Schedule 14D-9 with respect to the Offer.

Once filed, investors will be able to obtain the tender offer statement on Schedule TO, the offer to purchase, the Solicitation/Recommendation Statement of the Company on Schedule 14D-9 and related materials with respect to the Offer and the proposed Merger, free of charge at the website of the SEC at www.sec.gov or from the information agent named in the Offer materials. Investors may also obtain, at no charge, the documents filed with or furnished to the SEC by the Company under the "Investors" section of the Company's website at www.cincor.com.

Stockholders and Investors are strongly advised to read these documents when they become available, including the Solicitation/Recommendation Statement of the Company on Schedule 14D-9 and any amendments thereto, as well as any other documents relating to the Offer and the proposed Merger that are filed with the SEC, carefully and in their entirety prior to making any decisions with respect to whether to tender their Shares into the Offer because they contain important information, including the terms and conditions of the Offer and the proposed Merger.

Cautionary Statement Regarding Forward-Looking Statements

Certain statements either contained in or incorporated by reference into this document constitute forward-looking statements within the meaning of the federal securities laws. Any express or implied statements that do not relate to historical or current facts or matters are forward-looking statements. These forward-looking statements generally include statements that are predictive in nature and depend upon or refer to future events or

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conditions, including, but not limited to statements related to CinCor's business in general and the timing of completion of the transactions contemplated by the Merger Agreement by and among CinCor, Purchaser, and Parent, including the parties' ability to satisfy the conditions to the consummation of the Offer and the other conditions set forth in the Merger Agreement and the possibility of any termination of the Merger Agreement. Words such as "believes," "plans," "anticipates," "projects," "estimates," "expects," "intends," "strategy," "future," "opportunity," "may," "will," "should," "could," "potential," or similar expressions are intended to identify forward-looking statements. These forward-looking statements are based on CinCor's current plans, objectives, estimates, expectations and intentions, involve assumptions that may never materialize or may prove to be incorrect and inherently involve significant risks and uncertainties, including factors beyond CinCor's control, that could cause actual results, performance, or achievement to differ materially and adversely from those anticipated or implied in the statements, including, without limitation: uncertainties with respect to the timing of the Offer and the proposed Merger; uncertainties as to the number of shares of CinCor's common stock that will be tendered in the Offer; the risk that competing offers or acquisition proposals will be made; the possibility that various conditions to the consummation of the Offer or the proposed Merger may not be satisfied or waived, including that a governmental entity may prohibit, delay or refuse to grant approval for the consummation of the Offer or the proposed Merger at all or on acceptable terms or within expected timing; the risk that stockholder litigation in connection with the Offer or the proposed Merger may result in significant costs of defense, indemnification and liability; the effects of disruption from the transactions contemplated by the Merger Agreement on CinCor's business and the fact that the announcement and pendency of such transactions may make it more difficult to establish or maintain relationships with employees and business partners; the possibility that the Milestone will never be achieved and no milestone payment may be made; initial, interim, "top-line" and preliminary data from clinical trials announced or published from time to time may change; success in preclinical studies or earlier clinical trials may not be indicative of results in future clinical trials; enrollment and retention of patients in clinical trials could be delayed; CinCor relies and will rely on third parties to conduct, supervise and monitor existing clinical trials and potential future clinical trials; developments from the company's competitors and the marketplace for the company's products; and business, operations and clinical development timelines and plans may be adversely affected by the COVID-19 pandemic, geopolitical events, and macroeconomic conditions, including rising inflation and interest rates and uncertain credit and financial markets, and matters related thereto; and other risks and uncertainties affecting the company, including those described under the caption "Risk Factors" and elsewhere in CinCor's Annual Report on Form 10-K for the year ended December 31, 2021 filed with the SEC on March 22, 2022, CinCor's Quarterly Report on Form 10-Q for the three months ended March 31, 2022 filed with the SEC on May 10, 2022, CinCor's Quarterly Report on Form 10-Q for the three months ended June 30, 2022 filed with the SEC on August 8, 2022, CinCor's Quarterly Report on Form 10-Q for the three months ended September 30, 2022 filed with the SEC on November 3, 2022, and other filings and reports that CinCor may file from time to time with the SEC. Other risks and uncertainties of which CinCor is not currently aware may also affect CinCor's forward-looking statements and may cause actual results and the timing of events to differ materially from those anticipated. These risks and uncertainties may be amplified by macroeconomic conditions, including volatility and uncertainty in financial markets. All forward-looking statements contained in or incorporated by reference into this document speak only as of the date on which they were made and are based on management's assumptions and estimates as of such date. CinCor undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required by law.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.



Exhibit                                  Description

2.1*          Agreement and Plan of Merger, dated as of January 8, 2023, by and
            among CinCor Pharma, Inc., AstraZeneca Finance and Holdings Inc. and
            Cinnamon Acquisition, Inc.

99.1          Press Release of CinCor Pharma, Inc., dated January 9, 2023.

104         Cover Page Interactive Date File (embedded within the Inline XBRL
            document)


* Certain exhibits and schedules have been omitted pursuant to Item 601(b)(2) of

Regulation S-K. The Company agrees to furnish supplementally a copy of any

omitted exhibit or schedule to the SEC upon request; provided, however, that

the Company may request confidential treatment pursuant to Rule 24b-2 of the

Exchange Act for any schedule so furnished.

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