[Translation: Please note that the following purports to be a translation from the Japanese original Notice of Resolution of the 111th Annual General Meeting of Shareholders for the business term ended December 31, 2021 of Chugai Pharmaceutical Co., Ltd. prepared for the convenience of shareholders outside Japan with voting rights. However, in the case of any discrepancy between the translation and the Japanese original, the latter shall prevail.

(Securities Code: 4519)

March 29, 2022

To the Shareholders:

NOTICE OF RESOLUTION OF

THE 111th ANNUAL GENERAL MEETING OF SHAREHOLDERS

We are pleased to announce that the matters below were reported and resolved at the 111th Annual General Meeting of Shareholders of Chugai Pharmaceutical Co., Ltd. held today (the "AGM").

Yours very truly,

Osamu Okuda Representative Director, President & CEO

CHUGAI PHARMACEUTICAL CO., LTD. (the "Company")

1-1 Nihonbashi-Muromachi 2-chome, Chuo-ku, Tokyo

PARTICULARS

Matters Reported:

The Business Report for the Business Term (January 1, 2021 to December 31, 2021, the "Term"), Non-Consolidated Financial Statements for the Term, Consolidated Financial Statements for the Term, and the Report on the Results of Audit of the Consolidated Financial Statements by the Accounting Auditor and Audit & Supervisory Board

The contents of the above were reported.

Matters Resolved:

First Proposal Appropriation of Surplus

This item was approved and resolved as originally

proposed. Appropriation of surplus for the end of the

Term was decided to be JPY46 per share of common

stock of the Company, and JPY75,638,615,304 in an

aggregate amount.

Second Proposal

Partial Amendments to the Articles of Incorporation

This item was approved and resolved as originally proposed. The Company's Articles of Incorporation were amended as follows:

(Amended parts are underlined.)

Before Amendment

After Amendment

CHAPTER 3

GENERAL MEETING OF SHAREHOLDERS

(Disclosure on Internet of Reference Materials for General Meeting of Shareholders Deemed and Deemed Provision of that Information)

Article 15 If the Company discloses information relating to matters stated or indicated in reference documents, business report, accounting documents and consolidated financial statements (including Accounting Auditor's report and Audit & Supervisory Board Members' report relating to any such consolidated accounting documents) in connection with convening the General Meeting of Shareholders through the Internet pursuant to the Ordinance of the Ministry of Justice, the Company may deem that it has provided the same to shareholders.

(Newly established)

(Deleted)

Article 15 (Electronic Provision Measure, etc.)

1. The Company shall, when convening a General Meeting of Shareholders, take the electronic provision measure for information included in the reference document for General Meeting of Shareholders, etc. 2. Among the matters subject to the electronic provision measure, the Company may choose not to include all or part of the matters stipulated in the Ordinance of the Ministry of Justice in the paper copy to be sent to shareholders who have requested it by the record date for voting rights.

Before Amendment

After Amendment

(Newly established)

(Supplementary Provisions)

1. The deletion of Article 15 (Disclosure on Internet of Reference Materials for General Meeting of Shareholders Deemed and Deemed Provision of that Information) of the current Articles of Incorporation and the new establishment of the proposed Article 15 (Electronic Provision Measure, etc.) shall come into effect on September 1, 2022.

2. Notwithstanding the provisions of the preceding paragraph, Article 15 of the current Articles of Incorporation shall remain in force with respect to a General Meeting of Shareholders to be held on a date within six (6) months from September 1, 2022.

3. These supplementary provisions shall be deleted on the later of either the day on which six (6) months elapse from September 1, 2022 or the day on which three (3) months elapse from the day of the General Meeting of Shareholders set forth in the preceding paragraph.

Third Proposal Election of Four (4) Directors

This item was approved and resolved as originally

proposed. Two (2) Directors, namely, Osamu Okuda

and Mariko Y Momoi were reelected and assumed

office. Two (2) Directors, namely, Hisafumi Yamada

and Toshiaki Itagaki were newly elected and assumed

office.

Director Mariko Y Momoi is an Outside Director.

- End -

Directors and Audit & Supervisory Board Members

Based on the resolution by the Board of Directors and the Audit & Supervisory Board which were held after the AGM, Directors and Audit & Supervisory Board Members of the Company are as follows:

Representative Director, President & CEO

Osamu Okuda

reelected

Director

William N. Anderson

Director, Executive Vice President

Hisafumi Yamada

newly elected

Director

James H. Sabry

Director, Executive Vice President

Toshiaki Itagaki

newly elected

Full-time Audit & Supervisory Board Member

Atsushi Sato

Outside Director

Masayuki Oku

Full-time Audit & Supervisory Board Member

Yoshiaki Ohashi

Outside Director

Yoichiro Ichimaru

Outside Audit & Supervisory Board Member

Takaaki Nimura

Outside Director

Mariko Y Momoi

reelected

Outside Audit & Supervisory Board Member

Yuko Maeda

Director

Christoph Franz

Outside Audit & Supervisory Board Member

Kenichi Masuda

New management structure of the Company, as of April 1, 2022, will be as follows:

Executive Vice President

Tetsuya Yamaguchi

Vice President

Junichi Nezu

Executive Vice President

Junichi Ebihara

Vice President

Tsukasa Kusano

Executive Vice President

Shinji Hidaka

Vice President

Kaori Ouchi

Executive Vice President

Yoshiyuki Yano

Vice President

Shinya Takuma

Executive Vice President

Satoko Shisai

Vice President

Hitoshi Iikura

Senior Vice President

Mark Noguchi

Vice President

Masayoshi Higuchi

Vice President

Minoru Watanabe

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Chugai Pharmaceutical Co. Ltd. published this content on 29 March 2022 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 30 March 2022 11:14:01 UTC.