The board of directors of CARsgen Therapeutics Holdings Limited announced that Dr. Chunhai FAN (‘Dr. Fan') tendered his resignation as an independent non-executive Director with effect from January 11, 2023 due to his other business commitments which require more of his attention and dedication. Following the resignation of Dr. Fan, he also ceased to act as the chairman of the remuneration committee (the ‘Remuneration Committee') and a member of each of the audit committee (the ‘Audit Committee') and the nomination and corporate governance committee (the ‘Nomination and Corporate Governance Committee') of the Company.