Bio-Techne Corporation announced that Lunaphore, a Bio-Techne brand, will have its technologies featured in several presentations by prominent research centers at the Society for Immunotherapy of Cancer's (SITC) 38th Annual Meeting, taking place in San Diego, November 1-5, 2023. The recent studies will demonstrate the unmatched spatial biology capabilities of the company's universal, end-to-end COMET?? product suite, addressing complex biological questions from various research areas.

COMET?? is the only fully automated, high-throughput, hyperplex platform ensuring scalability and reproducibility without the need to conjugate primary antibodies, making panel design much more flexible and faster than any other hyperplex solution. Lunaphore's sponsored symposia will provide novel insights into the optimization of innovative anti-cancer therapy approaches for head and neck squamous cell carcinoma (HNSCC).

Researchers from the collaborative research project between the Earle A. Chiles Research Institute a division of Providence Cancer Institute, and Lunaphore will present the results of a hyperplex-based characterization of the tumor microenvironment (TME) in response to combined immunotherapy and stereotactic ablative radiation therapy (iSABR) neoadjuvant treatment of HNSCC, facilitated by the COMET? platform. The presentation will discuss strategies for rapid hyperplex sequential immunofluorescence (seqIF?) panel development and optimization, as well as methodologies for high-throughput data analytics.

The novel seqIF? method allows an unprecedented analysis of the immune compartment and potentially increases the clinical success of such therapies. Additionally, poster presentations will highlight how research institutes use their off-the-shelf antibodies on COMET?

to map immune and tumoral cells in lymphomas and various cancer tissues with the seqIF? approach. Furthermore, a poster of industry partnership will demonstrate proof-of-concept COMET?

workflow for same-slide, fully automated multiomics analysis of the TME. Lunaphore's scientists will be available at booth #530 to provide live demonstrations of the COMET? system and access to raw staining images of various cancer types.