Applied DNA Sciences, Inc. and Alphazyme LLC (Alphazyme) announced the successful conclusion of the companies' previously announced Linea? RNAP manufacturing scale-up agreement. The joint process development project resulted in an over 70% reduction in Linea RNAP manufacturing costs and the manufacture of a quantity of Linea RNAP sufficient to support Applied DNA's anticipated near-term demand for critical starting material for mRNA production.