Item 7.01 Regulation FD Disclosure.

On December 13, 2019, Alector, Inc. (the "Company") issued a press release regarding updates in the Company's clinical and research programs to be shared at its R&D Day on December 13, 2019 and a separate press release announcing the appointment of Dr. Richard Scheller and Dr. Thomas Südhof as co-chairs of the Company's Strategic Portfolio Advice and Review Committee (SPARC). A copy of the press releases are furnished as Exhibit 99.1 and Exhibit 99.2, respectively, to this Current Report on Form 8-K and are hereby incorporated by reference into this Item 7.01 and shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to liabilities of that section, nor shall such information and exhibit be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such a filing.

Item 8.01 Other Events.

In connection with Dr. Scheller's service and engagement as a co-chair of SPARC, the Board determined that Dr. Scheller is no longer considered "independent" under the rules of NASDAQ and the Securities and Exchange Commission. On December 6, 2019, the Board re-established the Compensation Committee and Nominating and Corporate Governance Committee as follows:

Compensation Committee

Mr. David Wehner (Chairperson)

Mr. Louis J. Lavigne, Jr.

Nominating and Corporate Governance Committee

Mr. Terry McGuire (Chairperson)

Dr. Kristine Yaffe

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

Exhibit No. Description 99.1 Press Release dated December 13, 2019. 99.2 Press Release dated December 13, 2019.

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