180 Life Sciences Corp. announced on May 7, 2024, Dr. James N. Woody resigned as member of the board of directors the company effective the same date and entered into a Separation and Release Agreement with the company (the Woody Separation Agreement). On May 7, 2024, Dr. Jonathan Rothbard resigned as Chief Scientific Officer of the Company effective the same date and entered into a Separation and Release Agreement with the Company (the Rothbard Separation Agreement).

Mr. Steinman also agreed to step down as executive chairman of the board of directors and will instead just serve as a member of the board of directors, provided that on May 7, 2024, Dr. Steinman was appointed as a member of the strategy and alternatives committee of the company.