Yield10 Bioscience, Inc. announced the results from the company’s 2018 Field Tests of C3003, a novel yield trait, in canola, Camelina and soybean. Yield10 is targeting step-changes of 10-20% in the evaluation and development of novel traits to increase seed yield in commercially important crops. In summary, the C3003 trait produced seed yield increases of up to 11% in the best lines of canola tested. Based on these results, the Company will progress C3003 in canola into the commercial development phase in 2019. The key activities to be completed during this next phase include development of additional commercial quality events in elite canola germplasm, execution of multi-site, multi-year field studies and development of regulatory data as appropriate. The 2018 Field Tests of C3003 were conducted at sites in Canada. The main objectives of the studies were to evaluate the performance of the novel lead yield trait gene C3003 in Camelina and canola, and to bulk up seed for soybean studies planned for 2019. Highlights from the studies include: Canola results: In Yield10’s 2018 Field Tests, the C3003 Gen 2.0 yield trait was tested for the first time in canola. The best C3003 Gen 2.0 canola lines showed an increase in seed yield of 11% as compared to control plants, a statistically significant outcome. In C3003 Gen 2.0 canola plants, the weight of an individual seed (measured using 1000 seeds) was similar to control plants, an expected outcome using the Gen 2.0 version of the C3003 trait. Camelina results: In Yield10’s 2018 Field Tests, the C3003 Gen 2.0 yield trait was tested in Camelina. Challenging weather conditions affected the results from the Camelina field trial. However, trends observed with the best Camelina C3003 Gen 2.0 lines support the canola observation that seed yields can be increased with the C3003 Gen 2.0 trait, particularly under drought conditions. The Company plans to further investigate the potential for C3003 to provide drought tolerance in oilseed and other commercial row crops. Soybean seed production: In the 2018 Field Tests, Yield10 met its objective of producing field grown seed for C3003 Gen 1.0 and Gen. 2.0 soybean plants. This seed will be used to conduct field tests of C3003 in soybean in the 2019 growing season. Further analysis underway: Yield10 researchers are conducting a comprehensive analysis of the 2018 field tests and will assess a range of additional data including gene expression, oil content and fatty acid composition produced in the C3003 containing plant lines.