The board of directors of Transcenta Holding Limited announced that Dr. Michael Ming Shi (" Dr. Shi "), the current Chief Medical Officer of the Company, has tendered his resignation with effect from July 31, 2022 for personal reasons. Dr. Shi has confirmed that there is no disagreement between him and the Company, and there are no matters that need to be brought to the attention of The Stock Exchange of Hong Kong Limited and the shareholders of the Company in relation to his resignation. The Company confirms that the medical operation related matters of the Company are all in an orderly manner and the departure of Dr. Shi will not have any adverse effect on the operations of the Company.

The Company has appointed a new Chief Medical Officer with senior leadership experience from another multinational corporation to be on board in August. The Company will disclose the details of new Chief Medical Officer in the subsequent announcement.