Corporate Overview
December 2021
©SPARC -For Discussion Purposes Only
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SPARC timeline
Built a robust R&D engine over 15 years
Integrated translation advancing standard of care in difficult-to-treat diseases
Incubated out of Sun Pharma, India's largest pharmaceutical company Spun out in 2007 to an independent listed entity Focus on exploratory programs and capability development
Initial focus on Medicinal | US FDA Approvals of | |
Chemistry and Formulations | Xelpros and Elepsia | |
Success with Lipodox | NCEs enter clinical | |
Multiple delivery systems | Development | |
innovations | Focus on strategic | |
Substantial investments in | partnering to access early | |
discovery & translational | science | |
development | ||
Growing NCE pipeline
3 more NDA submissions Forays into ADCs & Immunofusions
Poised to grow its multimodality platform in CNS, Oncology & Immunology
2007-2010 | 2011-2014 | 2015-2019 | 2020 & beyond | ||||||||||
Trading/Financial Summary | |||||||||||||
31.3% | |||||||||||||
$4 | $3.40 | ||||||||||||
$2 | |||||||||||||||||||
Share Price $ (as of 12/10/21) | $3.40 | ||||||||||||||||||
Premium / (Discount) to 52-Week High | (20%) | ||||||||||||||||||
Equity Value, T USD Mn | $892 | ||||||||||||||||||
Less : Cash USD Mn | (11) | ||||||||||||||||||
Plus : Debt USD Mn | 20 | ||||||||||||||||||
$0 | Enterprise Value USD Mn | $901 | |||||||||||||||||
Dec-20 | Feb | -21 Apr | -21 Jun | -21 Aug | -21 Oct | -21 | Dec | -21 |
SPARC © 2021 | 3 |
Investment highlights
4 Clinical Stage Programs Targeting Areas of High Unmet Need
Targeting large addressable patient populations with USD 20Bn+ combined peak sales potential in 6 indications within Oncology, Neurology, and Immunology
Discovery & Development Across Validated & Novel Biology in Order to Balance the Risk
Multi-modal portfolio covering small and large molecules and conjugated entities
10+ preclinical programs including an ADC program expected to enter the clinic in 2023
Proven High Quality R&D Organization with Capital-Efficient Global Operations
350+ scientists across 4 research centers including USD 400Mn invested to date 2 USFDA approvals for internally developed assets
3 NDAs targeted for submission in 2022
Highly Flexible Model to Maximize Shareholder Value
Partnerships to maximize large commercial potential and provide non-dilutive capital
Maximize multi-TA opportunity and preserve optionality for spin-offs
Experienced Management Team and Globally Recognized Scientific Advisory Board
ADC = Antibody Drug Conjugate | TA = Therapeutic Area | USFDA = United States Food and Drug Administration | NDA = New Drug Approval
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Pipeline overview & key milestones
Asset / Program | MoA | Indication | Discovery Preclinical | Phase 1 | Phase 2 | Phase 3/ | Upcoming | Partner | |||
Registration Study | Catalyst | ||||||||||
Parkinson's | PoC data from | ||||||||||
PROSEEK study | |||||||||||
Disease | |||||||||||
in 2023 | |||||||||||
Vodobatinib | c-ABL | Lewy Body | PoC data in 2023 | ||||||||
(SCC-138) | Inhibitor | Dementia1 | |||||||||
Alzheimer's | |||||||||||
Disease | |||||||||||
Vodobatinib | BCR-ABL | Refractory | Pivotal data | ||||||||
(SCO-088) | Inhibitor | CML | in 2024 | ||||||||
SCO-120 | SERD | Metastatic | Phase 1 data | ||||||||
Breast Cancer | in 2023 | ||||||||||
Psoriasis | Phase 2 | ||||||||||
data in 2023 | |||||||||||
Vibozilimod | Selective | Atopic | Phase 2 data | ||||||||
(SCD-044) | S1PR1 agonist | Dermatitis | in 2023 | ||||||||
Alopecia | |||||||||||
Areata | |||||||||||
Undisclosed | TAA-1 | Multiple | IND Filing | ||||||||
Tumors | Targeted 2023 | ||||||||||
Preclinical Assets 10+ preclinical assets under development to ensure a robust pipeline for future growth | |||||||||||
Neurology | Oncology | Immunology |
1. Investigator Initiated Study | MoA = Mechanism of Action | PoC = Proof of Concept | CML = Chronic Myeloid Leukemia | SERD = Selective Estrogen Receptor Degrader S1PR1 = Sphingosine-1-Phosphate Receptor 1 | IND = Investigational New Drug | TAA-1 = Tumor Associated Antigen-1
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Sun Pharma Advanced Research Company Limited published this content on 28 December 2021 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 28 December 2021 10:36:06 UTC.