- Roivant will develop RVT-2001 for the treatment of transfusion-dependent anemia in patients with lower-risk myelodysplastic syndromes
- Roivant JPM presentation scheduled for
Monday, January 10 , at2:15 p.m. ET
RVT-2001 is an orally available small molecule modulator of splicing factor 3B subunit 1 (SF3B1) with over 80 human subjects exposed to date. Under the terms of the agreement, Eisai will receive an upfront payment, development and regulatory milestone payments, and royalties on sales revenue for RVT-2001.
Roivant plans to develop RVT-2001 as a first-in-class therapy for transfusion-dependent anemia in patients with lower-risk myelodysplastic syndromes (MDS). The company intends to conduct a robust open-label expansion of an ongoing clinical trial for RVT-2001 (ClinicalTrials.gov Identifier: NCT02841540) this year.
Additional details on RVT-2001 and the company’s development plan will be provided during Roivant’s presentation at the 40th Annual
About Anemia in Lower-Risk MDS
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic malignancies characterized by cytopenias and abnormal blood cells. For patients with lower-risk MDS, anemia due to ineffective erythropoiesis leads to fatigue, dizziness, shortness of breath, and other symptoms which disrupt daily life. Time-consuming repeat red blood cell transfusions can result in iron overload and end-organ damage and current treatment options are ineffective for many patients.
About
Roivant's mission is to improve the delivery of healthcare to patients by treating every inefficiency as an opportunity. Roivant develops transformative medicines faster by building technologies and developing talent in creative ways, leveraging the Roivant platform to launch "Vants" – nimble and focused biopharmaceutical and health technology companies. For more information, please visit www.roivant.com.
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Contacts Investors Roivant Investor Relations ir@roivant.com MediaPaul Davis Roivant Sciences paul.davis@roivant.com
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