On December 31, 2018, Organogenesis Inc. and Prime Merger Sub, LLC entered into an amendment to the credit agreement, dated as of March 21, 2017, by and among Organogenesis, the lenders party thereto and Silicon Valley Bank, as administrative agent. This eighth amendment to credit agreement and amendment to consent agreement dated as of December 31, 2018 is entered into by and among Organogenesis Inc., Prime Merger Sub, LLC (Prime, and together with Organogenesis, each individually a Borrower and, collectively, the Borrowers), the several banks and other financial institutions or entities that are parties hereto as Lenders (each a Lender and, collectively, the Lenders), SILICON VALLEY BANK (SVB), as the Issuing Lender and the Swingline Lender, and SVB, as administrative agent and collateral agent for the Lenders (in such capacities, the Administrative Agent).