On February 22, 2022, Dr. Nilesh Kumar, Ph.D., notified the Board of Directors (the “Board”) of Morphic Holding, Inc. (the “Company”) of his decision to retire from the Board and resign as a member of the Board and the Company's Audit and Nominating and Governance Committees, respectively. Dr. Kumar's decision to resign was not related to any disagreement with the Company over any of its operations, policies, or practices.